IDENTIFICATION OF GENES THAT REGULATE TYPE-III SECRETION SYSTEM I OF VIBRIO PARAHAEMOLYTICUS IN RESPONSE TO HOST-CELL CONTACT

Thesis (Ph.D.), College of Veterinary Medicine, Washington State UniversityVibrio parahaemolyticus pandemic serotype O3:K6 causes acute gastroenteritis, wound infections and septicemia in humans. This organism encodes two type - III secretion systems (T3SS1 and T3SS2) of which host - cell cytotoxicity has been attributed to T3SS1. The purpose of this study is to identify factors responsible for regulating T3SS1 induction in response to host - cell contactCollege of Veterinary Medicine, Washington State Universit