FGF23 markers of mineral metabolism in subjects with preserved renal function

Introduction and Aims: FGF23 is a bone-derived hormone that regulates phosphate homeostasis. FGF23 is elevated in CKD and independently associated with poor renal and cardiovascular outcomes and mortality. The study of FGF23 in subjects with normal renal function has received little attention thus far. Methods: We examined in a large, population-based study with 1128 participants the associations of FGF23 with markers of mineral metabolism and renal function