In this study, reversed phase liquid chromatographic columns packed with superficially porous material made of a carbon core and nanodiamond-polymer shell were evaluated for the analytical characterization of proteins. The emphasis was put on the impact of pore size on the kinetic performance when analyzing large molecules. Three different types of columns possessing an average pore size of 120, 180, and 250Å were thus evaluated. As expected, the peak capacities were improved with the 180 and above all the 250Å pore size, while the kinetic performance achieved with the 120Å were systematically lower. It was also shown that a trifluoroacetic acid (TFA) concentration of 0.3-0.5% was required when analyzing proteins, to achieve suitable peak s...
Reversed phase liquid chromatography (RPLC) of therapeutic monoclonal antibodies (mAbs) is often per...
The chromatographic performance of a new brand of shell particles is compared to that of a conventio...
Recent developments in chromatographic supports and instrumentation for liquid chromatography (LC) a...
In this study, reversed phase liquid chromatographic columns packed with superficially porous materi...
The separation of large biomolecules such as proteins or monoclonal antibodies (mAbs) by RPLC can be...
Ultra-high performance liquid chromatography is a vital tool for proteomics and pharmaceutical analy...
The type of the stationary phase for reversed-phase liquid chromatography significantly affects the ...
This review paper discusses the success of columns packed with superficially porous particles (SPP) ...
A new size exclusion chromatography column packed with 1.7 µm particles articles and possessing 200 ...
The separation performance of a chromatographic system is often described in terms of column efficie...
Various recent wide-pore reversed-phase stationary phases were studied for the analysis of intact mo...
The objective of this study was to evaluate the potential of sub-2μm totally porous particles and su...
A number of advances have taken place in the last decade in the area of support materials for high p...
A wide-pore silica-based superficially porous material with a high coverage phenyl bonding was evalu...
At their optimum flow, sub-3 μm superficially porous or " shell" particles demonstrate similar effic...
Reversed phase liquid chromatography (RPLC) of therapeutic monoclonal antibodies (mAbs) is often per...
The chromatographic performance of a new brand of shell particles is compared to that of a conventio...
Recent developments in chromatographic supports and instrumentation for liquid chromatography (LC) a...
In this study, reversed phase liquid chromatographic columns packed with superficially porous materi...
The separation of large biomolecules such as proteins or monoclonal antibodies (mAbs) by RPLC can be...
Ultra-high performance liquid chromatography is a vital tool for proteomics and pharmaceutical analy...
The type of the stationary phase for reversed-phase liquid chromatography significantly affects the ...
This review paper discusses the success of columns packed with superficially porous particles (SPP) ...
A new size exclusion chromatography column packed with 1.7 µm particles articles and possessing 200 ...
The separation performance of a chromatographic system is often described in terms of column efficie...
Various recent wide-pore reversed-phase stationary phases were studied for the analysis of intact mo...
The objective of this study was to evaluate the potential of sub-2μm totally porous particles and su...
A number of advances have taken place in the last decade in the area of support materials for high p...
A wide-pore silica-based superficially porous material with a high coverage phenyl bonding was evalu...
At their optimum flow, sub-3 μm superficially porous or " shell" particles demonstrate similar effic...
Reversed phase liquid chromatography (RPLC) of therapeutic monoclonal antibodies (mAbs) is often per...
The chromatographic performance of a new brand of shell particles is compared to that of a conventio...
Recent developments in chromatographic supports and instrumentation for liquid chromatography (LC) a...