FXYD7, the first brain- and isoform-specific regulator of Na,K-ATPase: biosynthesis and function of its posttranslational modifications
- Crambert, G.
- Beguin, P.
- Uldry, M.
- Monnet-Tschudi, F.
- Horisberger, J. D.
- Garty, H.
- Geering, K.
Publication date
April 2003
DOI ISSN
0077-8923 Citation count (estimate)
15Abstract
The FXYD protein family has recently been defined as a result of the search for homologues of the Na,K-ATPase gamma subunit, CHIF, and phospholemman in EST and gene data banks. FXYD7 has been seen to have a role as a brain- and isozyme-specific regulator of Na/K-ATPase. In this study, the biosynthesis, membrane topology, nature, and role of the processing of FXYD7 are investigated
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