BACKGROUND: Dexamethasone-induced changes in radioresistance have previously been observed by several authors. Here, we examined effects of dexamethasone on resistance to ionizing radiation in 10 additional human cell lines and strains, and on resistance to carboplatin and paclitaxel in 13 fresh tumor samples. MATERIAL AND METHODS: Eight human carcinoma cell lines, a glioblastoma cell line and a strain of normal human diploid fibroblasts were arbitrarily chosen for these in-vitro studies. Effects on radiosensitivity were assessed using a conventional colony formation assay. Effects on resistance to the drugs were investigated prospectively (ATP cell viability assay) using 13 fresh tumor samples from consecutive patients operated for ovarian...
PURPOSE: We hypothesized that glucocorticoids may enhance tumor radiosensitivity by increasing tumor...
[[abstract]]Glucocorticoids (GCs) are commonly co-administered with cisplatin in the treatment of pa...
Purpose: Glucocorticoids (GCs) are often administered prior to any chemotherapeutics to prevent the ...
BACKGROUND: Inactivation of p53 by binding to simian virus 40-T antigen (SV40-T) and human papilloma...
Glucocorticoids (GCs), which act on stress pathways, are well-established in the co-treatment of dif...
AbstractGlucocorticoids (GCs), which act on stress pathways, are well-established in the co-treatmen...
Purpose: Dexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) ...
Dexamethasone (Dex) is widely used in the management of leukemia and lymphoma. While Dex is commonly...
Abstract Background Chemotherapy for pancreatic carcinoma often has severe side effects that limit i...
<p>(<b>A</b>), Dexamethasone (DEXA) promotes human T98G and U251 glioma growth. Human T98G and U251 ...
PurposeDexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) pa...
The effect of dexamethasone on human non-small cell lung carcinoma in vitro and in vivo was investig...
BACKGROUND: Glucocorticoids are widely used for cancer patients, although they can reduce the effica...
Objectives: We evaluated the effects of irradiation, doxorubicin and dexamethasone on human PC-3 pro...
Glucocorticoids (GCs) are used in the treatment of cancer to induce programmed cell death in the tra...
PURPOSE: We hypothesized that glucocorticoids may enhance tumor radiosensitivity by increasing tumor...
[[abstract]]Glucocorticoids (GCs) are commonly co-administered with cisplatin in the treatment of pa...
Purpose: Glucocorticoids (GCs) are often administered prior to any chemotherapeutics to prevent the ...
BACKGROUND: Inactivation of p53 by binding to simian virus 40-T antigen (SV40-T) and human papilloma...
Glucocorticoids (GCs), which act on stress pathways, are well-established in the co-treatment of dif...
AbstractGlucocorticoids (GCs), which act on stress pathways, are well-established in the co-treatmen...
Purpose: Dexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) ...
Dexamethasone (Dex) is widely used in the management of leukemia and lymphoma. While Dex is commonly...
Abstract Background Chemotherapy for pancreatic carcinoma often has severe side effects that limit i...
<p>(<b>A</b>), Dexamethasone (DEXA) promotes human T98G and U251 glioma growth. Human T98G and U251 ...
PurposeDexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) pa...
The effect of dexamethasone on human non-small cell lung carcinoma in vitro and in vivo was investig...
BACKGROUND: Glucocorticoids are widely used for cancer patients, although they can reduce the effica...
Objectives: We evaluated the effects of irradiation, doxorubicin and dexamethasone on human PC-3 pro...
Glucocorticoids (GCs) are used in the treatment of cancer to induce programmed cell death in the tra...
PURPOSE: We hypothesized that glucocorticoids may enhance tumor radiosensitivity by increasing tumor...
[[abstract]]Glucocorticoids (GCs) are commonly co-administered with cisplatin in the treatment of pa...
Purpose: Glucocorticoids (GCs) are often administered prior to any chemotherapeutics to prevent the ...