Add to ORKGWe report the appearance of a factor V inhibitor in an 82-year-old female patient following abdominal surgery. This anomaly was totally corrected following 9-day treatment with i.v. immunoglobulins (0.4 g/kg/day), which allowed a needed further surgical intervention to be performed without hemorrhagic diathesis. The activity of this inhibitor was partly reversed by the in vitro addition of immunoglobulins, suggesting a concentration-effect relationship. This finding supports the hypothesis that anti-idiotypic antibodies could play a role in the therapeutic effect of immunoglobulins in such situations
A 39‐year‐old patient, suffering from severe haemophilia B and antibodies against factor IX, has twi...
The variable region (V region) of an antibody, the part of the molecule that binds to antigen, is it...
Significant progresss has been made in understanding the mechanisms by which intravenous immunoglobu...
We report the appearance of a factor V inhibitor in an 82-year-old female patient following abdomina...
A factor V inhibitor arose in a 79-year-old man within 1 month of an operation for a fractured leg. ...
Therapeutic preparations of polyspecific IgG obtained from plasma pools of a large number of normal ...
We report the case of an 86-year-old female with an unremarkable past history who suddenly developed...
third patient with this inhibitor that we have seen and the seventh patient reported in the English-...
Intravenous immunoglobulin (IVIG) preparations were initially introduced as replacement therapy in p...
In the present study we found that antiphospholipid activity in sera from patients with anticardioli...
Intravenous immunoglobulin was originally developed for the treatment of primary immunodeficiencies ...
SUMMARY This report describes a patient without evident underlying disease, in whom an acquired von ...
Acquired inhibitors to coagulation factors are rare, certainly those directed against factor V. A to...
Acquired inhibitors to Factor VIII in nonhaemophil-iac patients are rare, but serious, having an inc...
Anti-Factor VIII (FVIII) antibodies were prepared by a combination of salt precipitation, gel filtra...
A 39‐year‐old patient, suffering from severe haemophilia B and antibodies against factor IX, has twi...
The variable region (V region) of an antibody, the part of the molecule that binds to antigen, is it...
Significant progresss has been made in understanding the mechanisms by which intravenous immunoglobu...
We report the appearance of a factor V inhibitor in an 82-year-old female patient following abdomina...
A factor V inhibitor arose in a 79-year-old man within 1 month of an operation for a fractured leg. ...
Therapeutic preparations of polyspecific IgG obtained from plasma pools of a large number of normal ...
We report the case of an 86-year-old female with an unremarkable past history who suddenly developed...
third patient with this inhibitor that we have seen and the seventh patient reported in the English-...
Intravenous immunoglobulin (IVIG) preparations were initially introduced as replacement therapy in p...
In the present study we found that antiphospholipid activity in sera from patients with anticardioli...
Intravenous immunoglobulin was originally developed for the treatment of primary immunodeficiencies ...
SUMMARY This report describes a patient without evident underlying disease, in whom an acquired von ...
Acquired inhibitors to coagulation factors are rare, certainly those directed against factor V. A to...
Acquired inhibitors to Factor VIII in nonhaemophil-iac patients are rare, but serious, having an inc...
Anti-Factor VIII (FVIII) antibodies were prepared by a combination of salt precipitation, gel filtra...
A 39‐year‐old patient, suffering from severe haemophilia B and antibodies against factor IX, has twi...
The variable region (V region) of an antibody, the part of the molecule that binds to antigen, is it...
Significant progresss has been made in understanding the mechanisms by which intravenous immunoglobu...