Interferon-γ inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuberculosis (TB) biomarker for adults. This study aims to evaluate the potential of IP-10 diagnostics in children from Uganda, a high TB-endemic country. Methods. IP-10 was measured in the blood and urine concomitantly taken from children who were prospectively enrolled with suspected active TB, with or without HIV infection. Clinical/microbiological parameters and commercially available TB-immune assays (tuberculin skin test (TST) and QuantiFERON TB-Gold In-Tube (QFT-IT)) were concomitantly evaluated. Results. One hundred twenty-eight children were prospectively enrolled. The analysis was performed on 111 children: 80 (72%) of them were HIV-unin...
AbstractIntroductionControl of TB depends on early detection and treatment of active cases.Aim of th...
Objectives Biomarkers for tuberculosis (TB) diagnosis and clinical management are needed to defeat T...
The suboptimal sensitivity of Interferon (IFN)-γ-based in-vitro assays, especially in immunocompromi...
Interferon-y inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuber...
Interferon-γ inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuber...
Objectives. Interferon-γ inducible protein 10 (IP-10), either in blood or in urine, has been propose...
BACKGROUND: The blood based interferon-gamma release assays (IGRA) for the diagnosis of tuberculosis...
SummaryObjectiveThis study evaluated inducible protein 10 (IP-10) as a diagnostic biomarker for spec...
BACKGROUND: Prior to clinical trials of new TB drugs or therapeutic vaccines, it is necessary to dev...
BACKGROUND: The diagnosis of tuberculosis (TB) in children is challenging by the absence of a practi...
BACKGROUND: In the absence of a gold standard for the diagnosis of latent tuberculosis (TB) infectio...
OBJECTIVE: This study evaluated inducible protein 10 (IP-10) as a diagnostic biomarker for specific ...
Diagnosis of childhood tuberculosis (TB) is difficult in high TB burden settings. Interferon-gamma-i...
<div><p>Background</p><p>In the absence of a gold standard for the diagnosis of latent tuberculosis ...
Current tests of tuberculosis (TB) infection (tuberculin skin test (TST), interferon (IFN)-γ-release...
AbstractIntroductionControl of TB depends on early detection and treatment of active cases.Aim of th...
Objectives Biomarkers for tuberculosis (TB) diagnosis and clinical management are needed to defeat T...
The suboptimal sensitivity of Interferon (IFN)-γ-based in-vitro assays, especially in immunocompromi...
Interferon-y inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuber...
Interferon-γ inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuber...
Objectives. Interferon-γ inducible protein 10 (IP-10), either in blood or in urine, has been propose...
BACKGROUND: The blood based interferon-gamma release assays (IGRA) for the diagnosis of tuberculosis...
SummaryObjectiveThis study evaluated inducible protein 10 (IP-10) as a diagnostic biomarker for spec...
BACKGROUND: Prior to clinical trials of new TB drugs or therapeutic vaccines, it is necessary to dev...
BACKGROUND: The diagnosis of tuberculosis (TB) in children is challenging by the absence of a practi...
BACKGROUND: In the absence of a gold standard for the diagnosis of latent tuberculosis (TB) infectio...
OBJECTIVE: This study evaluated inducible protein 10 (IP-10) as a diagnostic biomarker for specific ...
Diagnosis of childhood tuberculosis (TB) is difficult in high TB burden settings. Interferon-gamma-i...
<div><p>Background</p><p>In the absence of a gold standard for the diagnosis of latent tuberculosis ...
Current tests of tuberculosis (TB) infection (tuberculin skin test (TST), interferon (IFN)-γ-release...
AbstractIntroductionControl of TB depends on early detection and treatment of active cases.Aim of th...
Objectives Biomarkers for tuberculosis (TB) diagnosis and clinical management are needed to defeat T...
The suboptimal sensitivity of Interferon (IFN)-γ-based in-vitro assays, especially in immunocompromi...