Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations

This work was supported by theMedical Research Council of the United Kingdom, Wellcome Trust, National Institute of Health Research, Barts and The London Charity, Royal Society, and Pfizer. L.C.H.-R. was supported by grants from the National Council of Science and Technology and the Secretariat of Public Education from the Mexican Government. C.P. is funded by the Wellcome Trust 095605/Z11/Z