A.S. is supported by The Chris Rokos Fellowship in Evolution and Cancer. B.W. is supported by the Geoffrey W. Lewis Post-Doctoral Training fellowship. This work was supported by the Wellcome Trust (105104/Z/14/Z). C.P.B. acknowledges funding from the Wellcome Trust through a Research Career Development Fellowship (097319/Z/11/Z). This work was supported by a Cancer Research UK Career Development Award to T.A.G. M.J.W. is supported by a UK Medical Research Council student fellowship
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
Cancer develops through a process of somatic evolution1,2. Sequencing data from a single biopsy repr...
Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic dat...
Next-generation sequencing data from human cancers are often difficult to interpret within the conte...
Background: All cancer arise as a result of a somatic mutation, several models have been developed t...
Methods for reconstructing tumor evolution are benchmarked in the DREAM Somatic Mutation Calling Tum...
Cancer is a disease of the genome, requiring mutation or epimutation of specific genes to develop. ...
The consensus conference was supported by Wellcome Genome Campus Advanced Courses and Scientific Con...
The catalogue of tumour-specific somatic mutations (SMs) is growing rapidly owing to the advent of n...
The cancer genome is shaped by three components of the evolutionary process: mutation, selection and...
Recently available cancer sequencing data have revealed a complex view of the cancer genome containi...
We develop a branching process with accumulating mutations to model neutral tumor evolution. Further...
All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer cl...
All cancers are caused by somatic mutations; however, understanding of the biological processes gene...
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
Cancer develops through a process of somatic evolution1,2. Sequencing data from a single biopsy repr...
Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic dat...
Next-generation sequencing data from human cancers are often difficult to interpret within the conte...
Background: All cancer arise as a result of a somatic mutation, several models have been developed t...
Methods for reconstructing tumor evolution are benchmarked in the DREAM Somatic Mutation Calling Tum...
Cancer is a disease of the genome, requiring mutation or epimutation of specific genes to develop. ...
The consensus conference was supported by Wellcome Genome Campus Advanced Courses and Scientific Con...
The catalogue of tumour-specific somatic mutations (SMs) is growing rapidly owing to the advent of n...
The cancer genome is shaped by three components of the evolutionary process: mutation, selection and...
Recently available cancer sequencing data have revealed a complex view of the cancer genome containi...
We develop a branching process with accumulating mutations to model neutral tumor evolution. Further...
All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer cl...
All cancers are caused by somatic mutations; however, understanding of the biological processes gene...
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
It is increasingly common in oncology practice to perform tumour sequencing using large cancer panel...
Cancer develops through a process of somatic evolution1,2. Sequencing data from a single biopsy repr...