This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.This paper documents how biomedical researchers in the United Kingdom understand and enact the idea of “openness.” This is of particular interest to researchers and science policy worldwide in view of the recent adoption of pioneering policies on Open Science and Open Access by the UK government – policies whose impact on and implications for research practice are in need of urgent evaluation, so as to decide on their eventual implementation elsewhere. This study is based on 22 in-depth interviews with UK researchers in systems biology, synthetic biology and bioinformatics, which were conducted between September 2013 and Febr...