We investigate the question: ``Can there be a non-continuous isomorphism between two profinite groups which are not topologically isomorphic?" On one end of the spectrum, we show that branch and semisimple profinite groups have no non-continuous automorphisms. On the other, many abelian pro-$p$ groups are abstractly but not topologically isomorphic. The question for countably-based profinite groups was totally answered in a previous publication. There are many examples of such groups which are abstractly but not topologically isomorphic: we give explicit constructions of such non-topological isomorphisms We used Pontryagian duality to reduce the question of classifying countably based abelian pro-$p$ groups to that of countable...