The ELR motif-containing α-chemokines, IL-8 (interleukin-8) and MGSA (melanoma growth stimulating activity) show angiogenic activity in vivo along with chemotaxis and mitogenicity in vitro. However, the in vivo angiogenic response of a related family member, NAP-2 (neutrophil activating factor-2) has not been fully elucidated. NAP-2 is a first line mediator of neutrophil chemotaxis as a part of the inflammatory response. Although NAP-2 and IL-8 signal through chemokine receptors CXCR1 and CXCR2, they differ in their ability to activate neutrophils. IL-8 is more potent than NAP-2 at stimulating degranulation, phospholipase D activation and MAC1 integrin expression. Activated platelets provide the protein precursor that is cleaved to form NAP...
Human neutrophils, the most abundant circulating leukocytes, are fundamental compo-nents of the host...
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involv...
We have identified and characterized a novel proangiogenic glycoprotein (NAP) with molecular weight ...
The ELR motif-containing α-chemokines, IL-8 (interleukin-8) and MGSA (melanoma growth stimulating ac...
ObjectivesWe sought to investigate the role of the CXC chemokine neutrophil-activating peptide-2 (NA...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
We reported the expression of angiopoietin Tie2 receptor on human neutrophils and the capacity of an...
ObjectivesWe sought to investigate the role of the CXC chemokine neutrophil-activating peptide-2 (NA...
<div><p>We reported the expression of angiopoietin Tie2 receptor on human neutrophils and the capaci...
Abstract: Contrary to their traditional character-ization as terminally differentiated effectors of ...
Abstract: Contrary to their traditional character-ization as terminally differentiated effectors of ...
Human neutrophils, the most abundant circulating leukocytes, are fundamental compo-nents of the host...
Human neutrophils, the most abundant circulating leukocytes, are fundamental components of the host ...
Human neutrophils, the most abundant circulating leukocytes, are fundamental compo-nents of the host...
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involv...
We have identified and characterized a novel proangiogenic glycoprotein (NAP) with molecular weight ...
The ELR motif-containing α-chemokines, IL-8 (interleukin-8) and MGSA (melanoma growth stimulating ac...
ObjectivesWe sought to investigate the role of the CXC chemokine neutrophil-activating peptide-2 (NA...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste ...
We reported the expression of angiopoietin Tie2 receptor on human neutrophils and the capacity of an...
ObjectivesWe sought to investigate the role of the CXC chemokine neutrophil-activating peptide-2 (NA...
<div><p>We reported the expression of angiopoietin Tie2 receptor on human neutrophils and the capaci...
Abstract: Contrary to their traditional character-ization as terminally differentiated effectors of ...
Abstract: Contrary to their traditional character-ization as terminally differentiated effectors of ...
Human neutrophils, the most abundant circulating leukocytes, are fundamental compo-nents of the host...
Human neutrophils, the most abundant circulating leukocytes, are fundamental components of the host ...
Human neutrophils, the most abundant circulating leukocytes, are fundamental compo-nents of the host...
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involv...
We have identified and characterized a novel proangiogenic glycoprotein (NAP) with molecular weight ...