Motivated by applications in production and computer-communication systems, we study an N-queue polling system, consisting of an inner part and an outer part, and where products receive service in batches. Type-i products arrive at the outer system according to a renewal process and accumulate into a type-i batch. As soon as Di products have accumulated, the batch is forwarded to the inner system where the batch is processed. The service requirement of a type-i batch is independent of its size Di. For this model we study the problem of determining the combination of batch sizes D(opt) that minimizes a weighted sum of the mean waiting times. This model does not allow for an exact analysis. Therefore, we propose a simple closed-form approxima...