抗生素抗性基因(antibiotic resistance genes,ARGs)作为一种新型的环境污染物,成为多个学科关注的焦点.其在不同环境介质中的扩散和传播具有极大的环境危害性,对人类健康造成严重威胁.插入序列共同区(insertion sequence common region,ISCR),是一种新发现的抗性基因传播元件,因其特殊的遗传结构,能够通过滚环复制及同源重组等机制移动邻近的任何DNA序列,是ARGs在不同DNA分子或不同种属细菌间水平传播的高效媒介.目前世界上发现了27种ISCR元件.大量间接证据表明,ISCR可能与许多耐药基因的移动和扩散有关,特别是多重耐药性(multi..
Antibiotic resistance and its environmental component are gaining more attention as part of combatin...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...
抗生素抗性基因(antibiotic resistance genes,ARGs)作为一种新型的环境污染物,成为多个学科关注的焦点.其在不同环境介质中的扩散和传播具有极大的环境危害性,对人类健康造成严...
目的:研究北京大学第一医院不动杆菌临床分离株耐药表型与基因型.方法:琼脂稀释法和E-test法测定13种抗菌药物对31株不动杆菌的最低抑茵浓度(MIC),PCR检测8种耐药相关基因并测序分析.结果:1...
目的研究大肠杆菌多重耐药操纵子(mar)住临床分离株中的表达.方法采用聚合酶链反应扩增大肠杆菌临床分离株染色体基因组中多重耐药操纵子,经Southern blot鉴定,用限制性内切酶酶切分析,以逆转录...
Backgrounds and aims: The evolution of multi-resistant pathogens is seriously threatening our abilit...
研究種目:基盤研究(C)研究期間:2018~2020課題番号:18K08428研究代表者:長野 則之研究者番号:00747371Other2018~2020年度科学研究費助成事業(基盤研究(C)研究成...
目的:伤寒沙门菌275主动外排系统acrAB全基因测序并分析其结构.方法:以伤寒沙门菌基因序列为参考设计引物,以PCR法对伤寒沙门菌275 acrAB全序列进行调取并测序.结果:伤寒沙门菌275 ac...
目的 调查北京大学第一医院致病性耐甲氧西林金黄色葡萄球菌SCCmec分型情况、耐药状况、PVL、TSST-1基因携带率,初步了解临床耐甲氧西林金黄色葡萄球菌的耐药原因,为临床感染控制提供依据.方法 收...
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs pose serious...
Functional metagenomic analysis of soil metagenomes is a method for uncovering as-yet unidentified m...
Antibiotic resistance genes have become highly mobile since the development of antibiotic chemothera...
Antibiotic resistance and its environmental component are gaining more attention as part of combatin...
難治性尿路感染症の成立要因には,基礎疾患,体内挿入物とそれに伴うbiofilm の形成などに加え,原因菌の薬剤耐性の問題が挙げられる。特に本来耐性傾向の強い緑膿菌が,抗緑膿菌製剤に耐性を獲得し多剤耐性...
Antibiotic resistance and its environmental component are gaining more attention as part of combatin...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...
抗生素抗性基因(antibiotic resistance genes,ARGs)作为一种新型的环境污染物,成为多个学科关注的焦点.其在不同环境介质中的扩散和传播具有极大的环境危害性,对人类健康造成严...
目的:研究北京大学第一医院不动杆菌临床分离株耐药表型与基因型.方法:琼脂稀释法和E-test法测定13种抗菌药物对31株不动杆菌的最低抑茵浓度(MIC),PCR检测8种耐药相关基因并测序分析.结果:1...
目的研究大肠杆菌多重耐药操纵子(mar)住临床分离株中的表达.方法采用聚合酶链反应扩增大肠杆菌临床分离株染色体基因组中多重耐药操纵子,经Southern blot鉴定,用限制性内切酶酶切分析,以逆转录...
Backgrounds and aims: The evolution of multi-resistant pathogens is seriously threatening our abilit...
研究種目:基盤研究(C)研究期間:2018~2020課題番号:18K08428研究代表者:長野 則之研究者番号:00747371Other2018~2020年度科学研究費助成事業(基盤研究(C)研究成...
目的:伤寒沙门菌275主动外排系统acrAB全基因测序并分析其结构.方法:以伤寒沙门菌基因序列为参考设计引物,以PCR法对伤寒沙门菌275 acrAB全序列进行调取并测序.结果:伤寒沙门菌275 ac...
目的 调查北京大学第一医院致病性耐甲氧西林金黄色葡萄球菌SCCmec分型情况、耐药状况、PVL、TSST-1基因携带率,初步了解临床耐甲氧西林金黄色葡萄球菌的耐药原因,为临床感染控制提供依据.方法 收...
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs pose serious...
Functional metagenomic analysis of soil metagenomes is a method for uncovering as-yet unidentified m...
Antibiotic resistance genes have become highly mobile since the development of antibiotic chemothera...
Antibiotic resistance and its environmental component are gaining more attention as part of combatin...
難治性尿路感染症の成立要因には,基礎疾患,体内挿入物とそれに伴うbiofilm の形成などに加え,原因菌の薬剤耐性の問題が挙げられる。特に本来耐性傾向の強い緑膿菌が,抗緑膿菌製剤に耐性を獲得し多剤耐性...
Antibiotic resistance and its environmental component are gaining more attention as part of combatin...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usag...