Photodissociation and dissociative photoionization mass spectrometry of proteins and noncovalent protein-ligand complexes.
- Canon, Francis
- Milosavljević, Aleksandar R,
- van Der Rest, Guillaume,
- Réfrégiers, Matthieu,
- Nahon, Laurent,
- Manchado-Sarni, Pascale
- Cheynier, Veronique,
- Giuliani, Alexandre,
DOIAbstract
Weight of evidence: Using synchrotron radiation, photo-fragmentation of an intrinsically disordered protein is probed and compared with classical tandem mass-spectrometry activation techniques. It provides excellent sequence coverage allowing the identification of the protein noncovalent binding sites
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