beta(2)-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D
- Trian, T
- Burgess, J
- Niimi, K
- Moir, L
- Ge, Q
- Berger, P
- Liggett, S
- Black, J
- Oliver, BG
Publication date
January 2011
DOI Publisher
Public Library of Science (PLoS)Abstract
Background and Objective: Asthma is associated with airway narrowing in response to bronchoconstricting stimuli and increased airway smooth muscle (ASM) mass. In addition, some studies have suggested impaired beta-agonist induced ASM relaxation in asthm
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