Sketch-photo synthesis plays an important role in sketch-based face photo retrieval and photo-based face sketch retrieval systems. In this paper, we propose an automatic sketch-photo synthesis and retrieval algorithm based on sparse representation. The proposed sketch-photo synthesis method works at patch level and is composed of two steps: sparse neighbor selection (SNS) for an initial estimate of the pseudoimage (pseudosketch or pseudophoto) and sparse-representation-based enhancement (SRE) for further improving the quality of the synthesized image. SNS can find closely related neighbors adaptively and then generate an initial estimate for the pseudoimage. In SRE, a coupled sparse representation model is first constructed to learn the map...