Accumulation of amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles in bone marrow: implications for local stromal cells
- Schulze, Frank
- Gramoun, Azza
- Crowe, Lindsey
- Dienelt, anke
- Akcan, Tugba
- Hofmann, Heinrich
- Vallée, Jean-Paul
- Duda, Georg N
- Ode, Andrea
Publication date
January 2015
DOI Publisher
Future Medicine Ltd ISSN
1743-5889 Citation count (estimate)
2Abstract
First, it will be investigated if amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles (A-PVA-SPIONs) are suitable for MRI contrast enhancement in bone marrow. Second, the impact of A-PVA-SPION exposure in vivo on the viability and key functions of local bone marrow stromal cells (BMSCs) will be investigated
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