When dealing with partially reconfigurable designs on field-programmable gate array, floorplanning represents a critical step that highly impacts system's performance and reconfiguration overhead. However, current vendor design tools still require the floorplan to be manually defined by the designer. Within this paper, we provide a novel floorplanning automation framework, integrated in the Xilinx tool chain, which is based on an explicit enumeration of the possible placements of each region. Moreover, we propose a genetic algorithm (GA), enhanced with a local search strategy, to automate the floorplanning activity on the defined direct problem representation. The proposed approach has been experimentally evaluated with a synthetic benchmar...