Fibroblast growth factor-23 and cardiovascular disease in the general population: the Multi-Ethnic Study of Atherosclerosis
- Kestenbaum, Bryan
- Sachs, Michael C
- Hoofnagle, Andy N
- Siscovick, David S
- Ix, Joachim H
- Robinson-Cohen, Cassianne
- Lima, Joao A C
- Polak, Joseph F
- Blondon, Marc
- Ruzinski, John
- Rock, Denise
- de Boer, Ian H
Publication date
January 2014
DOI Publisher
Ovid Technologies (Wolters Kluwer Health) ISSN
1941-3289Abstract
Fibroblast growth factor-23 (FGF-23) is a phosphate regulatory hormone that directly stimulates left ventricular hypertrophy in experimental models. The role of FGF-23 in cardiovascular disease development in the general population is unclear. We tested associations of FGF-23 with major subclinical and clinical cardiovascular disease outcomes in a large prospective cohort
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