Characterization of the anti‐factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence‐based immunoassay

Analysis of epitopic and isotypic profile of anti-FVIII antibodies in haemophilia A patients

Lapalud, Priscilla

September 2012

Le facteur VIII (FVIII) joue un rôle essentiel dans la coagulation sanguine. Lorsque le FVIII fait g...

IntroductionThe major complication of protein replacement therapy for haemophilia A is the developme...

A longitudinal evaluation of anti‐FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high‐titre inhibitor in haemophilia a patients

Montalvão, S. A. L.
Tucunduva, A. C.
Siqueira, L. H.
Sambo, A. L. A.
Medina, S. S.
Ozelo, M. C.

January 2021

The development of inhibitory antibodies against factor VIII (FVIII) (inhibitor) is the major compli...

Haemophilia

Introduction:Accurate diagnosis of an inhibitor, a neutralizing antibody to infused factor VIII (FVI...

Detection and Prediction of Factor VIII Antibody Formation in Congenital and Acquired Haemophilia A

Batty, Paul Andrew

May 2016

Factor VIII (FVIII) is a co-factor in the haemostatic system required for fibrin-rich clot formation...

Diagnostic accuracy study of a factor VIII ELISA for detection of factor VIII antibodies in congenital and acquired haemophilia A

Batty, Paul
Moore, Gary W
Platton, Sean
Maloney, James C
Palmer, Ben
Bowles, Louise
Pasi, K John
Rangarajan, Savita
Hart, Daniel P

October 2015

Antibody formation to factor VIII (FVIII) remains the greatest clinical and diagnostic challenge to ...

J Thromb Haemost

BackgroundThe Bethesda assay (BA) for measurement of factor VIII (FVIII) inhibitors called for quant...

Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications

Liping Luo
Qiaoyun Zheng
Zhenyu Chen
Zhenyu Chen
Meijuan Huang
Lin Fu
Jianda Hu
Qizhen Shi
Qizhen Shi
Qizhen Shi
Qizhen Shi
Yingyu Chen

December 2022

The development of coagulation factor VIII (FVIII) inhibitory antibodies is a serious complication i...

Prevalence of factor VIII inhibitors in haemophilia a patients who received factor VIII therapy

Shanthi, G

May 2018

BACKGROUND: Haemophilia A is X - linked congenital bleeding disorder caused by dysfunctional or def...

Association Experience

Am J Clin Pathol

October 2016

A b s t r a c t Quantification of inhibitory antibodies against infused factor VIII (FVIII) has an i...

A study of prospective surveillance for inhibitors among persons with haemophilia in the United States

Soucie, J. M.
Miller, C. H.
Kelly, F. M.
Payne, A. B.
Creary, M.
Bockenstedt, P. L.
Kempton, C. L.
Manco‐johnson, M. J.
Neff, A. T.

March 2014

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106128/1/hae12302.pd

A Longitudinal Evaluation Of Anti-fviii Antibodies Demonstrated Igg4 Subclass Is Mainly Correlated With High-titre Inhibitor In Haemophilia A Patients

Montalvao
S. A. L.
A. C.
L. H.
A. L. A.
S. S.
M. C.

June 2016

The development of inhibitory antibodies against factor VIII (FVIII) (inhibitor) is the major compli...

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

Lewis, Kenneth B.
Hughes, Richard J.
Epstein, Melinda S.
Josephson, Neil C.
Kempton, Christine L.
Kessler, Craig M.
Key, Nigel S.
Howard, Tom E.
Kruse-Jarres, Rebecca
Lusher, Jeanne M.
Walsh, Christopher E.
Watts, Raymond G.
Ettinger, Ruth A.
Pratt, Kathleen P.

January 2013

Evidence of antibody isotype/subtype switching may provide prognostic value regarding the state of i...

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

Lewis, Kenneth B.
Hughes, Richard J.
Epstein, Melinda S.
Josephson, Neil C.
Kempton, Christine L.
Kessler, Craig M.
Key, Nigel S.
Howard, Tom E.
Kruse-Jarres, Rebecca
Lusher, Jeanne M.
Walsh, Christopher E.
Watts, Raymond G.
Ettinger, Ruth A.
Pratt, Kathleen P.

January 2013

Evidence of antibody isotype/subtype switching may provide prognostic value regarding the state of i...

Detection of all anti-factor VIII antibodies in haemophilia A patients by the Bethesda assay and a more sensitive immunoprecipitation assay

Klinge, J
Auerswald, G
Budde, U
Klose, H
Kreuz, W
Lenk, H
Scandella, D

January 2001

Plasmas from 40 haemophilia A patients enrolled in a study by the paediatric group of the German Soc...

Analysis of epitopic and isotypic profile of anti-FVIII antibodies in haemophilia A patients

Lapalud, Priscilla

September 2012

Le facteur VIII (FVIII) joue un rôle essentiel dans la coagulation sanguine. Lorsque le FVIII fait g...

Haemophilia

IntroductionThe major complication of protein replacement therapy for haemophilia A is the developme...

A longitudinal evaluation of anti‐FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high‐titre inhibitor in haemophilia a patients

Montalvão, S. A. L.
Tucunduva, A. C.
Siqueira, L. H.
Sambo, A. L. A.
Medina, S. S.
Ozelo, M. C.

January 2021

The development of inhibitory antibodies against factor VIII (FVIII) (inhibitor) is the major compli...

Haemophilia

Introduction:Accurate diagnosis of an inhibitor, a neutralizing antibody to infused factor VIII (FVI...

Detection and Prediction of Factor VIII Antibody Formation in Congenital and Acquired Haemophilia A

Batty, Paul Andrew

May 2016

Factor VIII (FVIII) is a co-factor in the haemostatic system required for fibrin-rich clot formation...

Diagnostic accuracy study of a factor VIII ELISA for detection of factor VIII antibodies in congenital and acquired haemophilia A

Batty, Paul
Moore, Gary W
Platton, Sean
Maloney, James C
Palmer, Ben
Bowles, Louise
Pasi, K John
Rangarajan, Savita
Hart, Daniel P

October 2015

Antibody formation to factor VIII (FVIII) remains the greatest clinical and diagnostic challenge to ...

J Thromb Haemost

BackgroundThe Bethesda assay (BA) for measurement of factor VIII (FVIII) inhibitors called for quant...

Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications

Liping Luo
Qiaoyun Zheng
Zhenyu Chen
Zhenyu Chen
Meijuan Huang
Lin Fu
Jianda Hu
Qizhen Shi
Qizhen Shi
Qizhen Shi
Qizhen Shi
Yingyu Chen

December 2022

The development of coagulation factor VIII (FVIII) inhibitory antibodies is a serious complication i...

Prevalence of factor VIII inhibitors in haemophilia a patients who received factor VIII therapy

Shanthi, G

May 2018

BACKGROUND: Haemophilia A is X - linked congenital bleeding disorder caused by dysfunctional or def...

Association Experience

Am J Clin Pathol

October 2016

A b s t r a c t Quantification of inhibitory antibodies against infused factor VIII (FVIII) has an i...

A study of prospective surveillance for inhibitors among persons with haemophilia in the United States

Soucie, J. M.
Miller, C. H.
Kelly, F. M.
Payne, A. B.
Creary, M.
Bockenstedt, P. L.
Kempton, C. L.
Manco‐johnson, M. J.
Neff, A. T.

March 2014

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106128/1/hae12302.pd

A Longitudinal Evaluation Of Anti-fviii Antibodies Demonstrated Igg4 Subclass Is Mainly Correlated With High-titre Inhibitor In Haemophilia A Patients

Montalvao
S. A. L.
A. C.
L. H.
A. L. A.
S. S.
M. C.

June 2016

The development of inhibitory antibodies against factor VIII (FVIII) (inhibitor) is the major compli...

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

Lewis, Kenneth B.
Hughes, Richard J.
Epstein, Melinda S.
Josephson, Neil C.
Kempton, Christine L.
Kessler, Craig M.
Key, Nigel S.
Howard, Tom E.
Kruse-Jarres, Rebecca
Lusher, Jeanne M.
Walsh, Christopher E.
Watts, Raymond G.
Ettinger, Ruth A.
Pratt, Kathleen P.

January 2013

Evidence of antibody isotype/subtype switching may provide prognostic value regarding the state of i...

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

Lewis, Kenneth B.
Hughes, Richard J.
Epstein, Melinda S.
Josephson, Neil C.
Kempton, Christine L.
Kessler, Craig M.
Key, Nigel S.
Howard, Tom E.
Kruse-Jarres, Rebecca
Lusher, Jeanne M.
Walsh, Christopher E.
Watts, Raymond G.
Ettinger, Ruth A.
Pratt, Kathleen P.

January 2013

Evidence of antibody isotype/subtype switching may provide prognostic value regarding the state of i...

Detection of all anti-factor VIII antibodies in haemophilia A patients by the Bethesda assay and a more sensitive immunoprecipitation assay

Klinge, J
Auerswald, G
Budde, U
Klose, H
Kreuz, W
Lenk, H
Scandella, D

January 2001

Plasmas from 40 haemophilia A patients enrolled in a study by the paediatric group of the German Soc...

Analysis of epitopic and isotypic profile of anti-FVIII antibodies in haemophilia A patients

Lapalud, Priscilla

September 2012

Le facteur VIII (FVIII) joue un rôle essentiel dans la coagulation sanguine. Lorsque le FVIII fait g...

Haemophilia

IntroductionThe major complication of protein replacement therapy for haemophilia A is the developme...

A longitudinal evaluation of anti‐FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high‐titre inhibitor in haemophilia a patients

Montalvão, S. A. L.
Tucunduva, A. C.
Siqueira, L. H.
Sambo, A. L. A.
Medina, S. S.
Ozelo, M. C.

January 2021

The development of inhibitory antibodies against factor VIII (FVIII) (inhibitor) is the major compli...

Characterization of the anti‐factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence‐based immunoassay

Abstract

Extracted data

Characterization of the anti‐factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence‐based immunoassay

Abstract

Extracted data

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