Gene expression profiles of 4‐hydroxy‐N‐desmethyl‐tamoxifen (endoxifen)‐ and 4‐hydroxy‐tamoxifen (4OHTAM)‐treated human breast cancer cells determined by CDNA microarray analysis | ORKG Ask

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International audienceTo explore the mechanisms whereby estrogen and antiestrogen (tamoxifen (TAM)) ...

Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells

SCAFOGLIO C
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<p> (<b>A</b>) Venn diagram of genes whose expression levels were significantly altered by 1.5 fold ...

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Helland, Thomas
Gjerde, Jennifer
Dankel, Simon N
Fenne, Ingvild Sveinsgjerd
Skartveit, Linn
Drangevåg, Andreas
Bozickovic, Olivera
Flågeng, Marianne Hauglid
Søiland, Håvard
Mellgren, Gunnar
Lien, Ernst Asbjørn

January 2015

Introduction: Tamoxifen is an anti-estrogen drug used in treatment of Estrogen Receptor (ER) positiv...

Endoxifen’s Molecular Mechanisms of Action Are Concentration Dependent and Different than That of Other Anti-Estrogens

John R. Hawse
Malayannan Subramaniam
Muzaffer Cicek
Xianglin Wu
Anne Gingery
Sarah B. Grygo
Zhifu Sun
Kevin S. Pitel
Wilma L. Lingle
Matthew P. Goetz
James N. Ingle
Thomas C. Spelsberg

January 2012

Endoxifen, a cytochrome P450 mediated tamoxifen metabolite, is being developed as a drug for the tre...

Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells.

SCAFOGLIO C
AMBROSINO C
CICATIELLO L
ALTUCCI L
ARDOVINO M
BONTEMPO P
MEDICI N
MOLINARI AM
NEBBIOSO A
FACCHIANO A
CALOGERO R
ELKON R
MENINI N
PONZONE R
BIGLIA N
SISMONDI P
DE BORTOLI M
WEISZ, Alessandro

January 2006

Antiestrogens used for breast cancer (BC) treatment differ among each other for the ability to affec...

Integrative analysis of gene expression patterns predicts specific modulations of defined cell functions by estrogen and tamoxifen in MCF7 breast cancer cells.

Gadal, Franck
Starzec, Anna
Bozic, Christophe
Pillot-Brochet, Céline
Malinge, Sophie
Ozanne, V.
Vicenzi, J.
Buffat, Laurent
Perret, Gérard,
Iris, François
Crepin, Michel

February 2005

International audienceTo explore the mechanisms whereby estrogen and antiestrogen (tamoxifen (TAM)) ...

Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells

SCAFOGLIO C
AMBROSINO C
CICATIELLO L
ALTUCCI, Lucia
ARDOVINO M
BONTEMPO, Paola
MEDICI, Nicola
MOLINARI, Anna Maria
NEBBIOSO, Angela
FACCHIANO A
CALOGERO RA
ELKON R
MENINI N
PONZONE R
BIGLIA N
SISMONDI P
BORTOLI MD
WEISZ A.

January 2006

Antiestrogens used for breast cancer (BC) treatment differ among each other for the ability to affec...

Microarray analysis of endoxifen concentration-dependent changes in gene expression in the presence of estrogen and physiologically relevant levels tamoxifen and its metabolites.

John R. Hawse (227611)
Malayannan Subramaniam (227615)
Muzaffer Cicek (227597)
Xianglin Wu (277382)
Anne Gingery (277383)
Sarah B. Grygo (277384)
Zhifu Sun (60356)
Kevin S. Pitel (277385)
Wilma L. Lingle (216838)
Matthew P. Goetz (150701)
James N. Ingle (277386)
Thomas C. Spelsberg (227619)

January 2013

<p> (<b>A</b>) Venn diagram of genes whose expression levels were significantly altered by 1.5 fold ...