Distinct conformational behaviors of four mammalian dual‐flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles

Dynamic control of electron transfers in diflavin reductases.

Aigrain, L
Fatemi, F
Frances, O
Lescop, E
Truan, G

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Aigrain, Louise
Fatemi, Fataneh
Frances, Oriane
Lescop, Ewen
Truan, Gilles

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Gilles Truan
Ewen Lescop
Oriane Frances
Louise Aigrain
Fataneh Fatemi

November 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Distinct Conformational Behaviors of Four Mammalian Dual-Flavin Reductases (Cytochrome P450 Reductase, Methionine Synthase Reductase, Neuronal Nitric Oxide Synthase, Endothelial Nitric Oxide Synthase) Determine Their Unique Catalytic Profiles

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Tejero, Jesus
Kenney, Claire T.
Pearl, Naw M.
Im, Sang-Choul
Waskell, Lucy
Stuehr, Dennis J.

December 2014

Multidomain enzymes often rely on large conformational motions to function. However, the conformatio...

A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase

Frances, Oriane
Fatemi, Fataneh
Pompon, Denis
Guittet, Eric
Sizun, Christina
Pérez, Javier
Lescop, Ewen
Truan, Gilles

March 2015

AbstractDiflavin reductases are bidomain electron transfer proteins in which structural reorientatio...

Oral 1832-2 – Charge Pairing and Phosphorylation Regulate The Conformational Equilibrium and Switching Rates in Neuronal and Endothelial NO Synthase Flavoprotein Domains

Haque, Mohammad Mahfuzul
Ray, Sougata Sinha
Bayachou, Mekki
Stuehr, Dennis

November 2014

Electron flux through nitric oxide synthase reductase (NOSr) is thought to depend on conformational ...

Differences in a Conformational Equilibrium Distinguish Catalysis by the Endothelial and Neuronal Nitric-Oxide Synthase Flavoproteins

Ilagan, Robielyn P.
Tiso, Mauro
Konas, David
Hemann, Craig
Durra, Deborah
Hille, Russ
Stuehr, Dennis J.

July 2008

Nitric oxide (NO) is a physiological mediator synthesized by NO synthases (NOS). Despite their struc...

Charge-Pairing Interactions Control The Conformational Setpoint and Motions of The FMN Domain in Neuronal Nitric Oxide Synthase

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Fadlalla, Mohammed A.
Durra, Deborah
Stuehr, Dennis J.

January 2013

The NOS (nitric oxide synthase; EC 1.14.13.39) enzymes contain a C-terminal flavoprotein domain [NOS...

Charge-Pairing Interactions Control The Conformational Setpoint and Motions of The FMN Domain in Neuronal Nitric Oxide Synthase

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Fadlalla, Mohammed A.
Durra, Deborah
Stuehr, Dennis J.

January 2013

The NOS (nitric oxide synthase; EC 1.14.13.39) enzymes contain a C-terminal flavoprotein domain [NOS...

Structural basis for differential electron flux in human methionine synthase reductase and cytochrome P450 reductase

Meints, Carla Erin

May 2015

Human diflavin oxidoreductases, methionine synthase reductase (MSR) and cytochrome P450 reductase (C...

Structural basis for differential electron flux in human methionine synthase reductase and cytochrome P450 reductase

Meints, Carla Erin

January 2015

Human diflavin oxidoreductases, methionine synthase reductase (MSR) and cytochrome P450 reductase (C...

A perspective on conformational control of electron transfer in nitric oxide synthases

Hedison, Tobias M.
Hay, Sam
Scrutton, Nigel S.

September 2016

AbstractThis perspective reviews single molecule and ensemble fluorescence spectroscopy studies of t...

A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase

Frances, Oriane
Fatemi, Fataneh
Pompon, Denis
Guittet, Eric
Sizun, Christina
Pérez, Javier
Lescop, Ewen
Truan, Gilles

March 2015

AbstractDiflavin reductases are bidomain electron transfer proteins in which structural reorientatio...

A Second FMN Binding Site in Yeast NADPH-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases

Lamb, David C.
Kim, Youngchang
Yermalitskaya, Liudmila V.
Yermalitsky, Valery N.
Lepesheva, Galina I.
Kelly, Steven L.
Waterman, Michael R.
Podust, Larissa M.

January 2006

SummaryNADPH-cytochrome P450 reductase transfers two reducing equivalents derived from a hydride ion...

Dynamic control of electron transfers in diflavin reductases.

Aigrain, L
Fatemi, F
Frances, O
Lescop, E
Truan, G

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic control of electron transfers in diflavin reductases.

Aigrain, L
Fatemi, F
Frances, O
Lescop, E
Truan, G

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Aigrain, Louise
Fatemi, Fataneh
Frances, Oriane
Lescop, Ewen
Truan, Gilles

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Gilles Truan
Ewen Lescop
Oriane Frances
Louise Aigrain
Fataneh Fatemi

November 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Distinct Conformational Behaviors of Four Mammalian Dual-Flavin Reductases (Cytochrome P450 Reductase, Methionine Synthase Reductase, Neuronal Nitric Oxide Synthase, Endothelial Nitric Oxide Synthase) Determine Their Unique Catalytic Profiles

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Tejero, Jesus
Kenney, Claire T.
Pearl, Naw M.
Im, Sang-Choul
Waskell, Lucy
Stuehr, Dennis J.

December 2014

Multidomain enzymes often rely on large conformational motions to function. However, the conformatio...

A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase

Frances, Oriane
Fatemi, Fataneh
Pompon, Denis
Guittet, Eric
Sizun, Christina
Pérez, Javier
Lescop, Ewen
Truan, Gilles

March 2015

AbstractDiflavin reductases are bidomain electron transfer proteins in which structural reorientatio...

Oral 1832-2 – Charge Pairing and Phosphorylation Regulate The Conformational Equilibrium and Switching Rates in Neuronal and Endothelial NO Synthase Flavoprotein Domains

Haque, Mohammad Mahfuzul
Ray, Sougata Sinha
Bayachou, Mekki
Stuehr, Dennis

November 2014

Electron flux through nitric oxide synthase reductase (NOSr) is thought to depend on conformational ...

Differences in a Conformational Equilibrium Distinguish Catalysis by the Endothelial and Neuronal Nitric-Oxide Synthase Flavoproteins

Ilagan, Robielyn P.
Tiso, Mauro
Konas, David
Hemann, Craig
Durra, Deborah
Hille, Russ
Stuehr, Dennis J.

July 2008

Nitric oxide (NO) is a physiological mediator synthesized by NO synthases (NOS). Despite their struc...

Charge-Pairing Interactions Control The Conformational Setpoint and Motions of The FMN Domain in Neuronal Nitric Oxide Synthase

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Fadlalla, Mohammed A.
Durra, Deborah
Stuehr, Dennis J.

January 2013

The NOS (nitric oxide synthase; EC 1.14.13.39) enzymes contain a C-terminal flavoprotein domain [NOS...

Charge-Pairing Interactions Control The Conformational Setpoint and Motions of The FMN Domain in Neuronal Nitric Oxide Synthase

Haque, Mohammad Mahfuzul
Bayachou, Mekki
Fadlalla, Mohammed A.
Durra, Deborah
Stuehr, Dennis J.

January 2013

The NOS (nitric oxide synthase; EC 1.14.13.39) enzymes contain a C-terminal flavoprotein domain [NOS...

Structural basis for differential electron flux in human methionine synthase reductase and cytochrome P450 reductase

Meints, Carla Erin

May 2015

Human diflavin oxidoreductases, methionine synthase reductase (MSR) and cytochrome P450 reductase (C...

Structural basis for differential electron flux in human methionine synthase reductase and cytochrome P450 reductase

Meints, Carla Erin

January 2015

Human diflavin oxidoreductases, methionine synthase reductase (MSR) and cytochrome P450 reductase (C...

A perspective on conformational control of electron transfer in nitric oxide synthases

Hedison, Tobias M.
Hay, Sam
Scrutton, Nigel S.

September 2016

AbstractThis perspective reviews single molecule and ensemble fluorescence spectroscopy studies of t...

A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase

Frances, Oriane
Fatemi, Fataneh
Pompon, Denis
Guittet, Eric
Sizun, Christina
Pérez, Javier
Lescop, Ewen
Truan, Gilles

March 2015

AbstractDiflavin reductases are bidomain electron transfer proteins in which structural reorientatio...

A Second FMN Binding Site in Yeast NADPH-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases

Lamb, David C.
Kim, Youngchang
Yermalitskaya, Liudmila V.
Yermalitsky, Valery N.
Lepesheva, Galina I.
Kelly, Steven L.
Waterman, Michael R.
Podust, Larissa M.

January 2006

SummaryNADPH-cytochrome P450 reductase transfers two reducing equivalents derived from a hydride ion...

Dynamic control of electron transfers in diflavin reductases.

Aigrain, L
Fatemi, F
Frances, O
Lescop, E
Truan, G

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic control of electron transfers in diflavin reductases.

Aigrain, L
Fatemi, F
Frances, O
Lescop, E
Truan, G

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Aigrain, Louise
Fatemi, Fataneh
Frances, Oriane
Lescop, Ewen
Truan, Gilles

January 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Dynamic Control of Electron Transfers in Diflavin Reductases

Gilles Truan
Ewen Lescop
Oriane Frances
Louise Aigrain
Fataneh Fatemi

November 2012

Diflavin reductases are essential proteins capable of splitting the two-electron flux from reduced p...

Distinct conformational behaviors of four mammalian dual‐flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles

Abstract

Extracted data

Distinct conformational behaviors of four mammalian dual‐flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles

Abstract

Extracted data

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