Single‐molecule enzymology à la Michaelis–Menten
- Grima, Ramon
- Walter, Nils G.
- Schnell, Santiago
DOIAbstract
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102694/1/febs12663.pd
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102694/1/febs12663.pd
The ability to dynamically probe single enzymes allows the experimental investigation of enzyme kine...
The development of single-molecule tools has significantly impacted the way we think about biochemic...
Large arrays of homogeneous microwells each defining a femtoliter volume are a versatile platform fo...
Single enzyme molecules display inevitable, stochastic fluctuations in their catalytic activity. In ...
AbstractSingle enzyme molecules display inevitable, stochastic fluctuations in their catalytic activ...
The rate of product formation is an important measure of the speed of enzyme reactions. Classical st...
AbstractThis review traces the history and logical progression of methods for quantitative analysis ...
The potential of single-enzyme studies to unravel the complex energy landscape of these polymeric ca...
AbstractAn alternative theoretical approach to enzyme kinetics that is particularly applicable to si...
This paper summarizes our present theoretical understanding of single-molecule kinetics associated w...
This doctoral thesis explores the exciting new territory of single molecule spectroscopy in studying...
Enzymes are biological catalysts vital to life processes and have attracted century-long investigati...
Accurate measurement of the quantitative aspects of enzyme-catalysed reactions is critical for a dee...
Many in vivo enzymatic processes, such as those of the tissue factor pathway of blood coagulation, o...
Journal ArticleGiven the substantial computational requirements of stochastic simulation, approximat...
The ability to dynamically probe single enzymes allows the experimental investigation of enzyme kine...
The development of single-molecule tools has significantly impacted the way we think about biochemic...
Large arrays of homogeneous microwells each defining a femtoliter volume are a versatile platform fo...
Single enzyme molecules display inevitable, stochastic fluctuations in their catalytic activity. In ...
AbstractSingle enzyme molecules display inevitable, stochastic fluctuations in their catalytic activ...
The rate of product formation is an important measure of the speed of enzyme reactions. Classical st...
AbstractThis review traces the history and logical progression of methods for quantitative analysis ...
The potential of single-enzyme studies to unravel the complex energy landscape of these polymeric ca...
AbstractAn alternative theoretical approach to enzyme kinetics that is particularly applicable to si...
This paper summarizes our present theoretical understanding of single-molecule kinetics associated w...
This doctoral thesis explores the exciting new territory of single molecule spectroscopy in studying...
Enzymes are biological catalysts vital to life processes and have attracted century-long investigati...
Accurate measurement of the quantitative aspects of enzyme-catalysed reactions is critical for a dee...
Many in vivo enzymatic processes, such as those of the tissue factor pathway of blood coagulation, o...
Journal ArticleGiven the substantial computational requirements of stochastic simulation, approximat...
The ability to dynamically probe single enzymes allows the experimental investigation of enzyme kine...
The development of single-molecule tools has significantly impacted the way we think about biochemic...
Large arrays of homogeneous microwells each defining a femtoliter volume are a versatile platform fo...
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