The effect of Crataegus oxyacantha Ø on homocysteine levels in males

M.Tech.Cardiovascular disease and its complications accounts for about half of all deaths worldwide. As conventional risk factors do not successfully explain all of these cases, homocysteine (Hey) appears to be a new and promising field to investigate as an accompanying risk factor for the development of cardiovascular disease (Stanger et al., 2004). Hyperhomocysteinaemia, or elevated Hey levels, have been shown to be directly linked to the development of cardiovascular disease (Wald and Morris, 2002). Crataegus oxyaeantha Mother Tincture (0) has been used over centuries for various cardiovascular disease conditions and is considered to have cardio-protective properties (Rose and Treadway, 1999), however its effect on homocysteine levels has not been researched. The atm of this double-blind placebo-controlled study was to determine the effect of homoeopathically prepared Crataegus oxyaeantha (J on Hey levels in males aged 25-35 years of age by measuring Hey levels in the blood over a three week period. Participants attended an initial consultation where the procedure of the research was discussed, a short medical history was taken, and a full cardiovascular examination together with vital signs was assessed. Thereafter a pathology laboratory (Lancet laboratories) measured Hey levels of the participants. Those participants that qualified for the study were divided into two groups of fifteen. The experimental group received a 25mL bottle of Crataegus oxyaeantha 0 and the placebo group received a 25mL bottle of alcohol identical in appearance and taste. Participants were informed not to make any substantial changes to their diet and lifestyle. After three weeks a second Hey test was completed and a follow up consultation was scheduled. Collected data was statistically analyzed and a Chi Square goodness of fit test was utilized to determine if there was any significant decrease in Hey levels in the participating individuals. Preliminary findings suggest that Crataegus oxyaeantha (J was not effective in reducing plasma Hey levels in adult males with Hey levels of 6.3 mmoVL and higher, however more research over an extended period of time is needed to confirm these findings