Adolescence coincides with increased sensation-seeking and impulsive behavior, and is often the time of symptomatic onset for psychopathologies. We recorded single unit activity from the orbitofrontal cortex (OFC), nucleus accumbens (NAc), and dorsal striatum (DS) of adolescent and adult rats during an instrumental associative learning task.\ud \ud Striking age-related differences were observed in the neural encoding of salient events, especially reward. A smaller proportion of adolescent OFC neurons were inhibited compared to that of adults during reinforcement retrieval and at other points during the task. Diminished inhibitory responses in adolescent OFC during salient events may affect the coordination of activity and ultimately neurona...
ABSTRACTAdolescence is a period marked by changes in motivational and cognitive brain systems. Howev...
Adolescence is associated with a dramatic increase in risky and impulsive behaviors that have been a...
BACKGROUND: Adolescent risk-taking, including behaviors resulting in injury or death, has been attri...
Adolescence coincides with increased sensation-seeking and impulsive behavior, and is often the time...
Immaturities in adolescent reward processing are thought to contribute to poor decision making and i...
AbstractImmaturities in adolescent reward processing are thought to contribute to poor decision maki...
Adolescence is a developmental stage between childhood and adulthood associated with numerous brain ...
Adolescence has been characterized by risk-taking behaviors that can lead to fatal outcomes. This st...
Adolescence is a period marked by changes in motivational and cognitive brain systems. However, the ...
Background Elucidating the neurobiology of the adolescent brain is fundamental to our understanding ...
The relation between brain development across adolescence and adolescent risky behavior has attracte...
The relation between brain development across adolescence and adolescent risky behavior has attracte...
Adolescence is a developmental period characterized by increased reward-seeking behavior. Investigat...
Adolescent risk-taking, including behaviors resulting in injury or death, has been attributed in par...
Adolescence is a crucial developmental period characterized by specific behaviors reflecting the imm...
ABSTRACTAdolescence is a period marked by changes in motivational and cognitive brain systems. Howev...
Adolescence is associated with a dramatic increase in risky and impulsive behaviors that have been a...
BACKGROUND: Adolescent risk-taking, including behaviors resulting in injury or death, has been attri...
Adolescence coincides with increased sensation-seeking and impulsive behavior, and is often the time...
Immaturities in adolescent reward processing are thought to contribute to poor decision making and i...
AbstractImmaturities in adolescent reward processing are thought to contribute to poor decision maki...
Adolescence is a developmental stage between childhood and adulthood associated with numerous brain ...
Adolescence has been characterized by risk-taking behaviors that can lead to fatal outcomes. This st...
Adolescence is a period marked by changes in motivational and cognitive brain systems. However, the ...
Background Elucidating the neurobiology of the adolescent brain is fundamental to our understanding ...
The relation between brain development across adolescence and adolescent risky behavior has attracte...
The relation between brain development across adolescence and adolescent risky behavior has attracte...
Adolescence is a developmental period characterized by increased reward-seeking behavior. Investigat...
Adolescent risk-taking, including behaviors resulting in injury or death, has been attributed in par...
Adolescence is a crucial developmental period characterized by specific behaviors reflecting the imm...
ABSTRACTAdolescence is a period marked by changes in motivational and cognitive brain systems. Howev...
Adolescence is associated with a dramatic increase in risky and impulsive behaviors that have been a...
BACKGROUND: Adolescent risk-taking, including behaviors resulting in injury or death, has been attri...