Design, Synthesis and Characterization of Porous Materials made from Nucleobases and Metals

This research is aimed at designing and synthesizing porous biomolecule-based materials for biological applications, such as a drug delivery. As a first step in this direction, developing a rational synthetic method to control the coordination chemistry between nucleobases and metal ions with the aim of organizing nucleobases into structurally well-defined porous materials has been studied. As a result, several interesting frameworks have been synthesized and characterized so far. They exhibit not only interesting structures but also unique physical properties.Interestingly, many of the adenine binding motifs are somewhat analogous to various carboxylate motifs which have been extensively used in MOF chemistry, suggesting that adenine could be a very versatile molecule for the construction and design of new MOFs. Furthermore, the successful synthesis of a porous material with adenine is very significant because it proves that porous material with bio-molecules can be rationally designed and synthesized for target applications