Rapid and efficient method for the synthesis of acylals from aldehydes and their deprotection catalyzed by p-Toluene Sulphonic Acid (p-TSA)

A simple, rapid, and efficient method has been developed for the synthesis of acylals from aldehydes using acetic anhydride in the presence of a catalytic amount p-TSA at 25°C, and the deprotection of acylals using water and catalytic p-TSA under microwave irradiation has been achieved in excellent yields. Copyright © Taylor & Francis Group, LLC