Physical Therapy DepartmentChronic neuropathic pain is a common, debilitating consequence of spinal cord injury (SCI). Up to 94% of the SCI population suffers from SCI pain, with over half reporting it as their worst medical problem. Modern day methods of SCI pain management are ineffective. Recent evidence suggests that this pain is due, in part, to aberrant outgrowth of sensory neurons at and below the level of injury. We have previously shown that SCI results in phosphorylation (inhibition) of glycogen synthase kinase-3β (GSK-3β), a key regulator of neuronal growth. The purpose of this study was to characterize the time-dependent nature of SCI-induced sensory neuron outgrowth below the level of injury, and to establish an optimal timef...
Poster Session C40: Trauma - Spinal cord injury and regenerationAims: Demyelination is one of the ma...
About 12,000 people every year are diagnosed with spinal cord injuries (SCI), the majority of which ...
Axonal regeneration within the injured spinal cord is hampered by multiple inhibitory molecules in t...
Chronic neuropathic pain is a common, debilitating consequence of spinal cord injury (SCI). Up to 94...
Background Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of s...
Background Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of...
Background: Spinal cord injury (SCI) often leads to central pain syndrome, including hyperalgesia to...
Spinal cord injury (SCI) often leads to central pain syndrome including hyperalgesia to mechanical s...
Pain serves an important purpose in warning of potential or actual damage to the body. When the nerv...
P2X4 and P2X7 receptors play an important role in neuropathic pain after spinal cord injury. Regulat...
Spinal cord injury (SCI) results in neuronal damage and glial scar formation, leading to loss of fun...
© 2020, The Author(s). The inhibition of glycogen synthase kinase-3 (GSK-3) can induce neurogenesis,...
Most spinal cord injury (SCI) patients suffer from chronic pain. Effective therapy for this pain is ...
Objectives Responses of spinal progenitors to spinal cord stimulation (SCS) following spinal cord in...
With a high occurrence of spinal cord injuries (SCIs) per year in the United States, and a significa...
Poster Session C40: Trauma - Spinal cord injury and regenerationAims: Demyelination is one of the ma...
About 12,000 people every year are diagnosed with spinal cord injuries (SCI), the majority of which ...
Axonal regeneration within the injured spinal cord is hampered by multiple inhibitory molecules in t...
Chronic neuropathic pain is a common, debilitating consequence of spinal cord injury (SCI). Up to 94...
Background Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of s...
Background Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of...
Background: Spinal cord injury (SCI) often leads to central pain syndrome, including hyperalgesia to...
Spinal cord injury (SCI) often leads to central pain syndrome including hyperalgesia to mechanical s...
Pain serves an important purpose in warning of potential or actual damage to the body. When the nerv...
P2X4 and P2X7 receptors play an important role in neuropathic pain after spinal cord injury. Regulat...
Spinal cord injury (SCI) results in neuronal damage and glial scar formation, leading to loss of fun...
© 2020, The Author(s). The inhibition of glycogen synthase kinase-3 (GSK-3) can induce neurogenesis,...
Most spinal cord injury (SCI) patients suffer from chronic pain. Effective therapy for this pain is ...
Objectives Responses of spinal progenitors to spinal cord stimulation (SCS) following spinal cord in...
With a high occurrence of spinal cord injuries (SCIs) per year in the United States, and a significa...
Poster Session C40: Trauma - Spinal cord injury and regenerationAims: Demyelination is one of the ma...
About 12,000 people every year are diagnosed with spinal cord injuries (SCI), the majority of which ...
Axonal regeneration within the injured spinal cord is hampered by multiple inhibitory molecules in t...