Study of Radiographic Measurements of Metacarpophalangeal Lengths, Pattern Profile Analysis, and Skeletal Maturity Judging from Hand and Wrist Bones in Down Syndrome

Down syndrome (DS) is one of the most famous congenital anomaly syndromes，which has characteristic clinical features，including stocky hands and short fingers. The lengths of 19 tubular bones of the hand were measured on radiographs of 222 patients in DS. Between healthy Japanese children and DS，the pattern of the length order of bones on each finger was same. The metacarpophalangeal pattern profile analysis (MCPP) of DS is presented ; MCPP of male and female DS is very similar， overall shortening of the hand tubular bones， relatively shortening of 2nd proximal phalanx. By TW2 method， bone age was judged. The bone age was different from the clinological age in range between -6 months and +3 months. Skeletal maturity of DS was almost normal.医歯学総合研究科博士論文(医学) ; 学位取得日: 平成9年9月18