Address for correspondence:\ud Dr. Milena Velizarova;\ud Department of Clinical Laboratory and Clinical Immunology;\ud University Hospital “Alexandrovska”;\ud 1 G. Sofi yski str.; \ud 1431 Sofi a, Bulgaria;\ud tel.: +359 2 92 30 916 ;\ud e-mail: mvelizarova@abv.bgThe BCR/ABL detection infl uences diagnosis, prognosis and treatment\ud decisions in patients with chronic myeloid leukemia (CML) and acute lymphoblastic\ud leukemia (ALL). We studied the feasibility and the sensitivity of LSI BCR/ABL\ud dual-colour, dual-fusion probe as a usual assay for detection BCR-ABL gene fusion\ud in acute leukemia. A total of 3229 successfully hybridized interphase nuclei from 34\ud newly diagnosed patients with acute leukemias (12 AML and 22 ALL cases) wer...
W e have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q + a...
Leukemia is hematology malignancy caused by excess proliferation of hematopoetic or lymphoid cells. ...
Nowadays, the presence of specific genetic aberrations is progressively used for classification and ...
Recent advances in molecular genetics impact the health care and outcome of patients with acute lymp...
Recent advances in molecular genetics impact the health care and outcome of patients with acute lymp...
Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which res...
This study was aimed to verify the efficacy of home-made LSI bcr/abl ES probe for detection of bcr/a...
Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which res...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
The presence of BCR-ABL fusion genes has important diag-nostic and prognostic implications in chroni...
The Philadelphia chromosome (Ph) resulting from translocation t(9;22)(q34;q11) is observed in more t...
BCR-ABL fusion proteins show increased signaling through their ABL tyrosine kinase domain, which can...
Twenty-four adult Chinese patients with do nova acute lymphoblastic leukemia (ALL) were studied for ...
W e have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q + a...
Leukemia is hematology malignancy caused by excess proliferation of hematopoetic or lymphoid cells. ...
Nowadays, the presence of specific genetic aberrations is progressively used for classification and ...
Recent advances in molecular genetics impact the health care and outcome of patients with acute lymp...
Recent advances in molecular genetics impact the health care and outcome of patients with acute lymp...
Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which res...
This study was aimed to verify the efficacy of home-made LSI bcr/abl ES probe for detection of bcr/a...
Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which res...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
Philadelphia (Ph) chromosome-positive leukemias, with the bcr-abl gene translocation, have a dismal ...
The presence of BCR-ABL fusion genes has important diag-nostic and prognostic implications in chroni...
The Philadelphia chromosome (Ph) resulting from translocation t(9;22)(q34;q11) is observed in more t...
BCR-ABL fusion proteins show increased signaling through their ABL tyrosine kinase domain, which can...
Twenty-four adult Chinese patients with do nova acute lymphoblastic leukemia (ALL) were studied for ...
W e have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q + a...
Leukemia is hematology malignancy caused by excess proliferation of hematopoetic or lymphoid cells. ...
Nowadays, the presence of specific genetic aberrations is progressively used for classification and ...