A general catalyst for Suzuki-Miyaura and Sonogashira reactions of aryl and heteroaryl chlorides in water

We report the synthesis of 2-(3-sulfonatomesityl)-5-sulfonatoindenyl(dicyclohexylphosphine hydrate sodium salt and its use in palladium-catalyzed Suzuki-Miyaura and Sonogashira coupling reactions in water (and biphasic water-organic solvent mixtures(to prepare a variety of functionalized biaryls and aryl alkynes in excellent yield