Add to ORKGA novel functional probe bearing both a benzophenone moiety and a biotin moiety was synthesized in 5 steps with an overall yield of 9%. Photoaffinity labeling and biotin blot experiment with the probe and the crude protein extracts from Saccharomyces cerevisiae AS 2.399 revealed that the synthetic probe was attached to a number of proteins, providing a basis for further chemical proteomics research
Summary: Here, we describe a protocol for a photoaffinity labeling probe strategy for target deconvo...
Previously held under moratorium from 14th January 2020 until 22nd November 2022. GSK - held in Chem...
This thesis investigates the feasibility of a kinetic method to detect photoaffinity labeling of the...
A novel functional probe bearing both a benzophenone moiety and a biotin moiety was synthesized in 5...
Three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using on...
Two novel chemical probes each carrying an intact isoprenoid chain, a biotin tag and a benzophenone ...
Three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using on...
A chemical proteomic approach was developed for profiling the noncovalent interactome of isoprenoid ...
<div><p>A novel linker containing biotin, alkyne and benzophenone groups (<b>1</b>) was synthesized ...
Chemical proteomics is a branch of proteomics in order to decipher protein function and mechanism at...
We present a one-step Ugi reaction protocol for the expedient synthesis of photoaffinity probes for ...
The fluorophosphonate (FP) moiety attached to a biotin tag is a prototype chemical probe used to qua...
To study the interactions between oligonucleotides and proteins, an original photoaffinity radiolabe...
Target identification of biologically active molecules such as natural products, synthetic small mo...
The novel alpha-amino acid BpAib, a partially conformationally restricted analogue of the currently ...
Summary: Here, we describe a protocol for a photoaffinity labeling probe strategy for target deconvo...
Previously held under moratorium from 14th January 2020 until 22nd November 2022. GSK - held in Chem...
This thesis investigates the feasibility of a kinetic method to detect photoaffinity labeling of the...
A novel functional probe bearing both a benzophenone moiety and a biotin moiety was synthesized in 5...
Three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using on...
Two novel chemical probes each carrying an intact isoprenoid chain, a biotin tag and a benzophenone ...
Three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using on...
A chemical proteomic approach was developed for profiling the noncovalent interactome of isoprenoid ...
<div><p>A novel linker containing biotin, alkyne and benzophenone groups (<b>1</b>) was synthesized ...
Chemical proteomics is a branch of proteomics in order to decipher protein function and mechanism at...
We present a one-step Ugi reaction protocol for the expedient synthesis of photoaffinity probes for ...
The fluorophosphonate (FP) moiety attached to a biotin tag is a prototype chemical probe used to qua...
To study the interactions between oligonucleotides and proteins, an original photoaffinity radiolabe...
Target identification of biologically active molecules such as natural products, synthetic small mo...
The novel alpha-amino acid BpAib, a partially conformationally restricted analogue of the currently ...
Summary: Here, we describe a protocol for a photoaffinity labeling probe strategy for target deconvo...
Previously held under moratorium from 14th January 2020 until 22nd November 2022. GSK - held in Chem...
This thesis investigates the feasibility of a kinetic method to detect photoaffinity labeling of the...