Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles

  • Duan, Ying
  • Chen, Mu-Wang
  • Chen, Qing-An
  • Yu, Chang-Bin
  • Zhou, Yong-Gui
  • 周永贵
Publication date
January 2012
ISSN
1477-0520

Abstract

A series of 2-substituted 3-(toluenesulfonamidoalkyl)indoles was synthesized by application of (EtO)(2)POH or iodine as the catalyst, and was hydrogenated using chiral Pd catalyst, giving the 2,3-disubstituted indolines with up to 97% ee

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iodineChemical substance
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chiralBuilding
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