A novel magnetic mesoporous silica packed S-shaped microfluidic reactor for online proteolysis of low-MW proteome
- Min, Qianhao
- Zhang, Xiaoxia
- Wu, Ren'an
- Zou, Hanfa
- Zhu, Jun-Jie
- 朱俊杰
DOIAbstract
A novel magnetic mesoporous silica packed S-shaped microfluidic reactor for online proteolysis of low-MW proteomeMagnetic mesoporous silica with a magnetic cover and mesoporous core was synthesized, filled with trypsin and located in an S-shaped microfluidic reactor. High-molecular weight (MW) proteins were split to waste by fractionation, whilst low-MW proteins were retained on the chip to be digested
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