Publication date
January 2007
DOIAbstract
目的: 研究低水平铅暴露对大鼠学习和记忆的影响。方法:0.05%水平醋酸铅污染大鼠饮用水28天, 用Morris水迷宫试验测定大鼠的学习记忆功能。结果:在定位导航任务两组之间没有差异(P>0.05);在探索试验和工作记忆任务中, 铅暴露组和正常对照组大鼠成绩显著差异(P<0.01)。结论:铅暴露对大鼠空间参考记忆和工作记忆有明显损害作用, 对空间学习未见明显影
目的: 研究低水平铅暴露对大鼠学习和记忆的影响。方法:0.05%水平醋酸铅污染大鼠饮用水28天, 用Morris水迷宫试验测定大鼠的学习记忆功能。结果:在定位导航任务两组之间没有差异(P>0.05);在探索试验和工作记忆任务中, 铅暴露组和正常对照组大鼠成绩显著差异(P<0.01)。结论:铅暴露对大鼠空间参考记忆和工作记忆有明显损害作用, 对空间学习未见明显影
Lead (Pb2+) is a developmental neurotoxicant that causes lifelong cognitive deficiencies. Previous s...
Introduction & Objective: Numerous observations in clinical and preclinical studies indicate that th...
Lead (Pb) is a toxic metal that affects almost all human’s system and organs, with the nervous syste...
目的观察和探讨铅对大鼠海马C-fos基因表达及学习记忆的影响.方法选用健康大鼠30只,每天给醋酸铅灌胃1次,高剂量组0.2 g/(kg*d),低剂量组0.1 g/(kg*d),连续染毒3个月后,用Y型...
BACKGROUND: Studies have demonstrated that lead exposure can result in cognitive dysfunction and beh...
研究了铅染毒大鼠血液中铅与其他元素之间的关系.选取75只健康的4周龄雄性Sprague-Dawley大鼠(SD大鼠),随机分为25组,各组染毒剂量均不相同.在实验开始的第40、80、120天,分别从各...
目的探讨孕鼠铅染毒对仔鼠大脑皮层和海马一氧化氮(NO)含量的影响.方法采用腹腔注射方式于大鼠孕13～19 d 进行醋酸铅染毒,仔鼠出生后第一天检测大脑皮层及海马组织内蛋白质和NO含量.结果随染铅剂量的...
目的探讨孕鼠铅染毒对其仔鼠脑发育及脑组织蛋白质、丙二醛(MDA)及超氧化物歧化酶(SOD)的影响.方法采用腹腔注射方式于大鼠妊娠第13、16、19天进行醋酸铅染毒,每次腹腔注射5,20,40 mg/k...
目的: 观察中药复方驱铅灵浸膏粉对铅暴露动物学习和记忆损害的拮抗作用。方法: 将48 只SD 大鼠随机分成6 组, 除正常对照组和中药对照组大鼠外, 其余各组大鼠均连续饮用28 天0. 05% 的醋酸...
. These authors contributed equally to this work. Lead (Pb) is found to impair cognitive function. S...
Lead (Pb) is found to impair cognitive function. Synaptic structural plasticity is considered to be ...
目的:探讨消化道铅暴露对大鼠体内铅及其他金属元素含量的影响.方法:将SD大鼠随机分成对照组和不同剂量受试组,采用醋酸铅溶液隔天灌胃染毒,连续染毒5次后收集大鼠全血、尿液与粪便.用电感耦合等离子体质谱仪...
Critical periods of neural development occur during early postnatal life that correspond with increa...
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impai...
Background\ud \ud A complete explanation of the mechanisms by which Pb2+ exerts toxic effects on dev...
Lead (Pb2+) is a developmental neurotoxicant that causes lifelong cognitive deficiencies. Previous s...
Introduction & Objective: Numerous observations in clinical and preclinical studies indicate that th...
Lead (Pb) is a toxic metal that affects almost all human’s system and organs, with the nervous syste...
目的观察和探讨铅对大鼠海马C-fos基因表达及学习记忆的影响.方法选用健康大鼠30只,每天给醋酸铅灌胃1次,高剂量组0.2 g/(kg*d),低剂量组0.1 g/(kg*d),连续染毒3个月后,用Y型...
BACKGROUND: Studies have demonstrated that lead exposure can result in cognitive dysfunction and beh...
研究了铅染毒大鼠血液中铅与其他元素之间的关系.选取75只健康的4周龄雄性Sprague-Dawley大鼠(SD大鼠),随机分为25组,各组染毒剂量均不相同.在实验开始的第40、80、120天,分别从各...
目的探讨孕鼠铅染毒对仔鼠大脑皮层和海马一氧化氮(NO)含量的影响.方法采用腹腔注射方式于大鼠孕13～19 d 进行醋酸铅染毒,仔鼠出生后第一天检测大脑皮层及海马组织内蛋白质和NO含量.结果随染铅剂量的...
目的探讨孕鼠铅染毒对其仔鼠脑发育及脑组织蛋白质、丙二醛(MDA)及超氧化物歧化酶(SOD)的影响.方法采用腹腔注射方式于大鼠妊娠第13、16、19天进行醋酸铅染毒,每次腹腔注射5,20,40 mg/k...
目的: 观察中药复方驱铅灵浸膏粉对铅暴露动物学习和记忆损害的拮抗作用。方法: 将48 只SD 大鼠随机分成6 组, 除正常对照组和中药对照组大鼠外, 其余各组大鼠均连续饮用28 天0. 05% 的醋酸...
. These authors contributed equally to this work. Lead (Pb) is found to impair cognitive function. S...
Lead (Pb) is found to impair cognitive function. Synaptic structural plasticity is considered to be ...
目的:探讨消化道铅暴露对大鼠体内铅及其他金属元素含量的影响.方法:将SD大鼠随机分成对照组和不同剂量受试组,采用醋酸铅溶液隔天灌胃染毒,连续染毒5次后收集大鼠全血、尿液与粪便.用电感耦合等离子体质谱仪...
Critical periods of neural development occur during early postnatal life that correspond with increa...
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impai...
Background\ud \ud A complete explanation of the mechanisms by which Pb2+ exerts toxic effects on dev...
Lead (Pb2+) is a developmental neurotoxicant that causes lifelong cognitive deficiencies. Previous s...
Introduction & Objective: Numerous observations in clinical and preclinical studies indicate that th...
Lead (Pb) is a toxic metal that affects almost all human’s system and organs, with the nervous syste...
Add to ORKG