Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial function. We have recently found that MDSCs differentiate into a cardiomyocyte phenotype within a three-dimensional gel bioreactor. It is generally accepted that terminally differentiated myocardium or skeletal muscle only express cTn-I or sk-fMHC, respectively. Studies have shown the presence of non-cardiac muscle proteins in the developing myocardium or cardiac proteins in pathological skeletal muscle. In the current study, we tested the hypothesis that normal developing myocardium and skeletal...
AbstractThe Serum Response Factor (SRF) coactivator myocardin stimulates the transcription of multip...
BACKGROUND: Cellular cardiomyoplasty for myocardial infarction has been developed using various cell...
Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (h...
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate in...
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate in...
<p>The skeletal muscle fast myosin heavy chain (sk-fMHC) and cardiac troponin-I (cTn-I) expression w...
<p><b>Lane 1</b>: ED13; <b>Lane 2</b>: ED20; <b>Lane 3</b>: ND0; <b>Lane 4</b>: ND4; <b>Lane 5</b>: ...
Expression of cardiac troponin I (TnIcardiac) and slow skeletal troponin I (TnIslow) genes was analy...
Abstract—Cardiomyoplasty with skeletal myoblasts may benefit cardiac function after infarction. Rece...
<div><p>It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividin...
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus ...
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus ...
Heart failure results in significant cardiomyocyte (CM) loss, and post-natal mammalian heart has lim...
Fetal rat skeletal muscles express a troponin T (TnT) isoform similar to the TnT isoform expr...
Cardiomyopathies are rare but serious disorders that affect the heart muscle and require lifetime tr...
AbstractThe Serum Response Factor (SRF) coactivator myocardin stimulates the transcription of multip...
BACKGROUND: Cellular cardiomyoplasty for myocardial infarction has been developed using various cell...
Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (h...
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate in...
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate in...
<p>The skeletal muscle fast myosin heavy chain (sk-fMHC) and cardiac troponin-I (cTn-I) expression w...
<p><b>Lane 1</b>: ED13; <b>Lane 2</b>: ED20; <b>Lane 3</b>: ND0; <b>Lane 4</b>: ND4; <b>Lane 5</b>: ...
Expression of cardiac troponin I (TnIcardiac) and slow skeletal troponin I (TnIslow) genes was analy...
Abstract—Cardiomyoplasty with skeletal myoblasts may benefit cardiac function after infarction. Rece...
<div><p>It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividin...
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus ...
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus ...
Heart failure results in significant cardiomyocyte (CM) loss, and post-natal mammalian heart has lim...
Fetal rat skeletal muscles express a troponin T (TnT) isoform similar to the TnT isoform expr...
Cardiomyopathies are rare but serious disorders that affect the heart muscle and require lifetime tr...
AbstractThe Serum Response Factor (SRF) coactivator myocardin stimulates the transcription of multip...
BACKGROUND: Cellular cardiomyoplasty for myocardial infarction has been developed using various cell...
Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (h...