Add to ORKGHIV-1 infected individuals show a remarkable variation in virus replication and disease progression. Host cellular gene expression as a response to virus infection is directly correlated with disease patterns. Here, we examine the role of microRNAs on mRNA regulation and its effect in HIV-1 disease progression by performing a comparative microRNA and mRNA profiling.\ud Total RNA was extracted from subjects with high viral load (HVL)(>45,000 copies/ml), low viral load (LVL) (~<40 copies/ml), and uninfected controls. RNA was quality tested and then reverse transcribed and tested using a Megaplex Real-time PCR for the quantification of expression of 754 miRNAs, in addition to controls, using a high throughput array. Transcriptome profiling was...
BACKGROUND: The emerging relationship between microRNAs (miRNA) and viral-control is a topic of inte...
Background: MiRNAs inhibit HIV-1 expression by either modulating host innate immunity or by directly...
ABSTRACT The question of howHIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector ...
Background\ud Disease progression in the absence of therapy varies significantly in HIV-1 infected i...
Background\ud Disease progression in the absence of therapy varies significantly in HIV-1 infected i...
Background: Disease progression in the absence of therapy varies significantly in HIV-1 infected ind...
Host cells respond to exogenous infectious agents such as viruses, including HIV-1. Studies have eva...
While human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) share many similar traits, major d...
Our understanding of the complexity of gene regulation has significantly improved in the last decade...
Background: MiRNAs inhibit HIV-1 expression by either modulating host innate immunity or by directly...
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in sy...
ABSTRACT HIV infection of CD4+ T cells induces a range of host transcriptional changes in mRNAs as w...
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in sy...
Objective: MicroRNAs (miRNAs) are small noncoding RNAs involved in the posttranscriptional regulatio...
Background/Aims: The main obstacle to cure HIV infection is the existence of long-lasting latent res...
BACKGROUND: The emerging relationship between microRNAs (miRNA) and viral-control is a topic of inte...
Background: MiRNAs inhibit HIV-1 expression by either modulating host innate immunity or by directly...
ABSTRACT The question of howHIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector ...
Background\ud Disease progression in the absence of therapy varies significantly in HIV-1 infected i...
Background\ud Disease progression in the absence of therapy varies significantly in HIV-1 infected i...
Background: Disease progression in the absence of therapy varies significantly in HIV-1 infected ind...
Host cells respond to exogenous infectious agents such as viruses, including HIV-1. Studies have eva...
While human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) share many similar traits, major d...
Our understanding of the complexity of gene regulation has significantly improved in the last decade...
Background: MiRNAs inhibit HIV-1 expression by either modulating host innate immunity or by directly...
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in sy...
ABSTRACT HIV infection of CD4+ T cells induces a range of host transcriptional changes in mRNAs as w...
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in sy...
Objective: MicroRNAs (miRNAs) are small noncoding RNAs involved in the posttranscriptional regulatio...
Background/Aims: The main obstacle to cure HIV infection is the existence of long-lasting latent res...
BACKGROUND: The emerging relationship between microRNAs (miRNA) and viral-control is a topic of inte...
Background: MiRNAs inhibit HIV-1 expression by either modulating host innate immunity or by directly...
ABSTRACT The question of howHIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector ...