Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.
- Li De La Sierra, Inès
- Munier-Lehmann, Hélène
- Gilles, Anne-Marie
- Bârzu, Octavian
- Delarue, Marc
Publication date
February 2000
DOI Publisher
International Union of Crystallography (IUCr)Abstract
International audienceMycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6(5)22 or P6(1)22, with unit-cell parameters a = b = 76.62, c = 134.38 A and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 A resolution using synchrotron radiation
Add to ORKG