International audienceEarly interactions between lung dendritic cells (LDCs) and Mycobacterium tuberculosis, the etiological agent of tuberculosis, are thought to be critical for mounting a protective anti-mycobacterial immune response and for determining the outcome of infection. However, these interactions are poorly understood, at least at the molecular level. Here we show that M. tuberculosis enters human monocyte-derived DCs after binding to the recently identified lectin DC-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN). By contrast, complement receptor (CR)3 and mannose receptor (MR), which are the main M. tuberculosis receptors on macrophages (Mphis), appeared to play a minor role, if any, in mycobacterial...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
Mycobacterium tuberculosis possesses a variety of immunomodulatory factors that influence the host i...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
International audienceEarly interactions between lung dendritic cells (LDCs) and Mycobacterium tuber...
Mycobacterium tuberculosis represents a world-wide health risk and immunosuppression is a particular...
International audienceInteractions between dendritic cells and Mycobacterium tuberculosis, the aetio...
International audienceBACKGROUND: Interplays between Mycobacterium tuberculosis, the etiological age...
Dendritic cells (DCs) are vital in the defense against pathogens. However, it is becoming increasing...
DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface mark...
The C-type lectin dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegri...
Mycobacterium tuberculosis represents a worldwide health risk and although macrophages are primarily...
DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface mark...
Dendritic-cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN; CD209) has...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
Mycobacterium tuberculosis possesses a variety of immunomodulatory factors that influence the host i...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
International audienceEarly interactions between lung dendritic cells (LDCs) and Mycobacterium tuber...
Mycobacterium tuberculosis represents a world-wide health risk and immunosuppression is a particular...
International audienceInteractions between dendritic cells and Mycobacterium tuberculosis, the aetio...
International audienceBACKGROUND: Interplays between Mycobacterium tuberculosis, the etiological age...
Dendritic cells (DCs) are vital in the defense against pathogens. However, it is becoming increasing...
DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface mark...
The C-type lectin dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegri...
Mycobacterium tuberculosis represents a worldwide health risk and although macrophages are primarily...
DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface mark...
Dendritic-cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN; CD209) has...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...
Mycobacterium tuberculosis possesses a variety of immunomodulatory factors that influence the host i...
<p>DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface m...