Molecular Recognition of DNA Damage Sites by Apurinic/Apyrimidinic Endonucleases
- Braun, W. A.
Publication date
July 2005
DOI Publisher
Office of Scientific and Technical Information (OSTI)Abstract
The DNA repair/redox factor AP endonuclease 1 (APE1) is a multifunctional protein which is known to to be essential for DNA repair activity in human cells. Structural/functional analyses of the APE activity is thus been an important research field to assess cellular defense mechanisms against ionizing radiation
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