Wnt Antagonist, Secreted Frizzled-Related Protein 4 (sFRP4), Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Secreted frizzled-related protein 4: An angiogenesis inhibitor

Muley, A.
Majumder, S.
Kolluru, G.
Parkinson, S.
Viola, H.
Hool, L.
Arfuso, Frank
Ganss, R.
Dharmarajan, Arunasalam
Chatterjee, S.

January 2010

Wnt signaling is involved in developmental processes, cell proliferation, and cell migration. Secret...

Secreted frizzled related proteins: Implications in cancers

Surana, R.
Sikka, S.
Cai, W.
Shin, E.
Warrier, S.
Tan, H.
Arfuso, Frank
Fox, Simon
Dharmarajan, Arunasalam
Kumar, A.

January 2014

The Wnt (wingless-type) signaling pathway plays an important role in embryonic development, tissue h...

Expression Profile of Wnt/β-Catenin Signalling Molecules and the Wnt Antagonist Secreted Frizzled-Related Protein 4 in Apoptosis in Breast Cancer Tissue Micro-Arrays

Berry, A.
Charles, A.
Zeps, N.
Cregan, D.
Arfuso, Frank
Dharmarajan, Arunasalam

January 2014

Wnt proteins are often up-regulated in cancer. The secreted frizzled-related proteins (sFRPs) can ab...

Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells

Warrier, S.
Balu, S.
Kumar, Alan Prem
Michael, M.
Dharmarajan, Arunasalam

January 2014

Malignant gliomas have a highly tumorigenic subpopulation, termed cancer stem cells (CSCs), that dri...

Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Senthil Kumar
Alan Prem
Arunasalam Dharmarajan

October 2016

Arunasalam. 2014. Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherap...

Secreted frizzled-related protein 4 inhibits glioma stem-like cells by reversing epithelial to mesenchymal transition, inducing apoptosis and decreasing cancer stem cell properties

Bhuvanalakshmi, G.
Arfuso, Frank
Millward, M.
Dharmarajan, Arunasalam
Warrier, Sudha

January 2015

The Wnt pathway is integrally involved in regulating self-renewal, proliferation, and maintenance of...

Secreted Frizzled-Related Protein 4 Inhibits Glioma Stem-Like Cells by Reversing Epithelial to Mesenchymal Transition, Inducing Apoptosis and Decreasing Cancer Stem Cell Properties

Bhuvanalakshmi G (747982)
Frank Arfuso (696005)
Michael Millward (254402)
Arun Dharmarajan (92865)
Sudha Warrier (747983)

June 2015

<div><p>The Wnt pathway is integrally involved in regulating self-renewal, proliferation, and mainte...

Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines

Deshmukh, A.
Kumar, S.
Arfuso, Frank
Newsholme, Philip
Dharmarajan, Arunasalam

January 2017

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

Gurubharathi Bhuvanalakshmi
Naisarg Gamit
Manasi Patil
Frank Arfuso
Gautam Sethi
Arun Dharmarajan
Alan Prem Kumar
Sudha Warrier

December 2018

Background: Chemotherapeutic resistance of glioblastoma has been attributed to a self-renewing subpo...

Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: Metabolic state of cancer cells

Perumal, Vanathi
Pohl, S.
Keane, K.
Arfuso, Frank
Newsholme, Philip
Fox, Simon
Dharmarajan, Arun

January 2015

Malignant mesothelioma (MM) is an aggressive cancer, characterized by rapid progression, along with ...

Secreted frizzled-related protein 4 and its implications in cancer and apoptosis

Pohl, S.
Scott, R.
Arfuso, Frank
Perumal, V.
Dharmarajan, Arunasalam

January 2015

Secreted frizzled-related protein 4 (SFRP4) is a glycoprotein that acts as an antagonist of Wnt liga...

Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation

Kierulf-Vieira, Kirsten Strømme
Sandberg, Cecilie J.
Grieg, Zanina
Günther, Clara-Cecilie
Langmoen, Iver A.
Vik-Mo, Einar O.

January 2016

AbstractEvidence indicates that the growth of glioblastoma (GBM), the most common and malignant prim...

TO MESENCHYMAL TRANSITION

Sudha Warrier
Bhuvanalakshmi G
Frank Arfuso
Gunesh Rajan
Michael Millward
Arun Dharmarajan

October 2016

Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, ...

Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.

Francis Jacob
Kristjan Ukegjini
Sheri Nixdorf
Caroline E Ford
Jake Olivier
Rosmarie Caduff
James P Scurry
Rea Guertler
Daniela Hornung
Renato Mueller
Daniel A Fink
Neville F Hacker
Viola A Heinzelmann-Schwarz

BACKGROUND: Activation of the Wnt signaling pathway is implicated in aberrant cellular proliferation...

The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain

Perumal, Vanathi
Dharmarajan, Arunasalam
Fox, Simon

January 2017

Secreted frizzled related proteins (SFRPs) are a family of Wnt regulators which are frequently downr...

Secreted frizzled-related protein 4: An angiogenesis inhibitor

Muley, A.
Majumder, S.
Kolluru, G.
Parkinson, S.
Viola, H.
Hool, L.
Arfuso, Frank
Ganss, R.
Dharmarajan, Arunasalam
Chatterjee, S.

January 2010

Wnt signaling is involved in developmental processes, cell proliferation, and cell migration. Secret...

Secreted frizzled related proteins: Implications in cancers

Surana, R.
Sikka, S.
Cai, W.
Shin, E.
Warrier, S.
Tan, H.
Arfuso, Frank
Fox, Simon
Dharmarajan, Arunasalam
Kumar, A.

January 2014

The Wnt (wingless-type) signaling pathway plays an important role in embryonic development, tissue h...

Expression Profile of Wnt/β-Catenin Signalling Molecules and the Wnt Antagonist Secreted Frizzled-Related Protein 4 in Apoptosis in Breast Cancer Tissue Micro-Arrays

Berry, A.
Charles, A.
Zeps, N.
Cregan, D.
Arfuso, Frank
Dharmarajan, Arunasalam

January 2014

Wnt proteins are often up-regulated in cancer. The secreted frizzled-related proteins (sFRPs) can ab...

Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells

Warrier, S.
Balu, S.
Kumar, Alan Prem
Michael, M.
Dharmarajan, Arunasalam

January 2014

Malignant gliomas have a highly tumorigenic subpopulation, termed cancer stem cells (CSCs), that dri...

Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Senthil Kumar
Alan Prem
Arunasalam Dharmarajan

October 2016

Arunasalam. 2014. Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherap...

Secreted frizzled-related protein 4 inhibits glioma stem-like cells by reversing epithelial to mesenchymal transition, inducing apoptosis and decreasing cancer stem cell properties

Bhuvanalakshmi, G.
Arfuso, Frank
Millward, M.
Dharmarajan, Arunasalam
Warrier, Sudha

January 2015

The Wnt pathway is integrally involved in regulating self-renewal, proliferation, and maintenance of...

Secreted Frizzled-Related Protein 4 Inhibits Glioma Stem-Like Cells by Reversing Epithelial to Mesenchymal Transition, Inducing Apoptosis and Decreasing Cancer Stem Cell Properties

Bhuvanalakshmi G (747982)
Frank Arfuso (696005)
Michael Millward (254402)
Arun Dharmarajan (92865)
Sudha Warrier (747983)

June 2015

<div><p>The Wnt pathway is integrally involved in regulating self-renewal, proliferation, and mainte...

Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines

Deshmukh, A.
Kumar, S.
Arfuso, Frank
Newsholme, Philip
Dharmarajan, Arunasalam

January 2017

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

Gurubharathi Bhuvanalakshmi
Naisarg Gamit
Manasi Patil
Frank Arfuso
Gautam Sethi
Arun Dharmarajan
Alan Prem Kumar
Sudha Warrier

December 2018

Background: Chemotherapeutic resistance of glioblastoma has been attributed to a self-renewing subpo...

Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: Metabolic state of cancer cells

Perumal, Vanathi
Pohl, S.
Keane, K.
Arfuso, Frank
Newsholme, Philip
Fox, Simon
Dharmarajan, Arun

January 2015

Malignant mesothelioma (MM) is an aggressive cancer, characterized by rapid progression, along with ...

Secreted frizzled-related protein 4 and its implications in cancer and apoptosis

Pohl, S.
Scott, R.
Arfuso, Frank
Perumal, V.
Dharmarajan, Arunasalam

January 2015

Secreted frizzled-related protein 4 (SFRP4) is a glycoprotein that acts as an antagonist of Wnt liga...

Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation

Kierulf-Vieira, Kirsten Strømme
Sandberg, Cecilie J.
Grieg, Zanina
Günther, Clara-Cecilie
Langmoen, Iver A.
Vik-Mo, Einar O.

January 2016

AbstractEvidence indicates that the growth of glioblastoma (GBM), the most common and malignant prim...

TO MESENCHYMAL TRANSITION

Sudha Warrier
Bhuvanalakshmi G
Frank Arfuso
Gunesh Rajan
Michael Millward
Arun Dharmarajan

October 2016

Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, ...

Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.

Francis Jacob
Kristjan Ukegjini
Sheri Nixdorf
Caroline E Ford
Jake Olivier
Rosmarie Caduff
James P Scurry
Rea Guertler
Daniela Hornung
Renato Mueller
Daniel A Fink
Neville F Hacker
Viola A Heinzelmann-Schwarz

BACKGROUND: Activation of the Wnt signaling pathway is implicated in aberrant cellular proliferation...

The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain

Perumal, Vanathi
Dharmarajan, Arunasalam
Fox, Simon

January 2017

Secreted frizzled related proteins (SFRPs) are a family of Wnt regulators which are frequently downr...

Secreted frizzled-related protein 4: An angiogenesis inhibitor

Muley, A.
Majumder, S.
Kolluru, G.
Parkinson, S.
Viola, H.
Hool, L.
Arfuso, Frank
Ganss, R.
Dharmarajan, Arunasalam
Chatterjee, S.

January 2010

Wnt signaling is involved in developmental processes, cell proliferation, and cell migration. Secret...

Secreted frizzled related proteins: Implications in cancers

Surana, R.
Sikka, S.
Cai, W.
Shin, E.
Warrier, S.
Tan, H.
Arfuso, Frank
Fox, Simon
Dharmarajan, Arunasalam
Kumar, A.

January 2014

The Wnt (wingless-type) signaling pathway plays an important role in embryonic development, tissue h...

Expression Profile of Wnt/β-Catenin Signalling Molecules and the Wnt Antagonist Secreted Frizzled-Related Protein 4 in Apoptosis in Breast Cancer Tissue Micro-Arrays

Berry, A.
Charles, A.
Zeps, N.
Cregan, D.
Arfuso, Frank
Dharmarajan, Arunasalam

January 2014

Wnt proteins are often up-regulated in cancer. The secreted frizzled-related proteins (sFRPs) can ab...

Wnt Antagonist, Secreted Frizzled-Related Protein 4 (sFRP4), Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Abstract

Extracted data

Wnt Antagonist, Secreted Frizzled-Related Protein 4 (sFRP4), Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Abstract

Extracted data

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