Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Young-Seon Kim
Yoon-Mi Lee
Taek-In Oh
Dong Hoon Shin
Geon-Hee Kim
Sang-Yeon Kan
Hyeji Kang
Ji Hyung Kim
Byeong Mo Kim
Woo Jong Yim
Ji-Hong Lim

October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observ...

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Shrimali, D.
Shanmugam, M.
Kumar, Alan Prem
Zhang, J.
Tan, B.
Ahn, K.
Sethi, G.

January 2013

Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a natural occurring anthraquinone derivative isol...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser Yue
Rajendran, Peramaiyan
Manu, Kanjoormana Aryan
Perumal, Ekambaram
Li, Feng
Shanmugam, Muthu K.
Siveen, Kodappully Sivaraman
Park, Joo In
Ahn, Kwang Seok
Hui, Kam Man
Kumar, Alan Prem
Sethi, Gautam

October 2013

Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL in...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma.

Kanjoormana Aryan Manu
Muthu K Shanmugam
Tina H Ong
Aruljothi Subramaniam
Kodappully Sivaraman Siveen
Ekambaram Perumal
Ramar Perumal Samy
Pradeep Bist
Lina H K Lim
Alan Prem Kumar
Kam M Hui
Gautam Sethi

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Kanjoormana Aryan Manu
Muthu K. Shanmugam
Tina H. Ong
Aruljothi Subramaniam
Ekambaram Perumal
Ramar Perumal Samy
Pradeep Bist
Lina H. K. Lim
Alan Prem Kumar
Kam M. Hui
Gautam Sethi

August 2016

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

Manu, K.
Shanmugam, M.
Ong, T.
Subramahniam, A.
Siveen, K.
Perumal, E.
Samy, R.
Bist, P.
Lim, L.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

Subramaniam, Aruljothi
Shanmugam, Muthu K.
Ong, Tina H.
Li, Feng
Perumal, Ekambaram
Chen, Luxi
Vali, Shireen
Abbasi, Taher
Kapoor, Shweta
Ahn, Kwang Seok
Kumar, Alan Prem
Hui, Kam Man
Sethi, Gautam

October 2013

Article on emodin inhibiting growth and inducing apoptosis in an orthotopic hepatocellular carcinoma...

Emodin suppresses CXCR4 in HCC cells.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

A, The chemical structure of emodin. B, Western blot analysis of CXCR4 and HER2 expression in HCC...

Emodin suppresses lung metastasis and CXCR4 expression in orthotopic mice model.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

Spontaneous metastatic model of human liver cancer cells orthotopically implanted in nude mice. C...

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

Chin-Mu Hsu

[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer...

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

Subramaniam, A.
Shanmugam, M.
Ong, T.
Li, F.
Perumal, E.
Chen, L.
Vali, S.
Abbasi, T.
Kapoor, S.
Ahn, K.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

BACKGROUND AND PURPOSE: Aberrant activation of STAT3 is frequently encountered and promotes prolifer...

Emodin suppresses migration and invasion of HepG2 cells.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

A, Wound-healing assay was performed for evaluating the inhibitory effect of emodin on HepG2 cell...

Emodin represses TWIST1-induced epithelial-mesenchymal transition in head and neck squamous cell carcinoma cells through the inhibition of β-catenin and Akt pathways

Tzong-Der Way

[[abstract]]Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer dea...

Emodin represses TWIST1-induced epithelial-mesenchymal transition in head and neck squamous cell carcinoma cells through the inhibition of β-catenin and Akt pathways

魏宗德

[[abstract]]Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer dea...

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Young-Seon Kim

October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observ...

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Young-Seon Kim
Yoon-Mi Lee
Taek-In Oh
Dong Hoon Shin
Geon-Hee Kim
Sang-Yeon Kan
Hyeji Kang
Ji Hyung Kim
Byeong Mo Kim
Woo Jong Yim
Ji-Hong Lim

October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observ...

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Shrimali, D.
Shanmugam, M.
Kumar, Alan Prem
Zhang, J.
Tan, B.
Ahn, K.
Sethi, G.

January 2013

Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a natural occurring anthraquinone derivative isol...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser Yue
Rajendran, Peramaiyan
Manu, Kanjoormana Aryan
Perumal, Ekambaram
Li, Feng
Shanmugam, Muthu K.
Siveen, Kodappully Sivaraman
Park, Joo In
Ahn, Kwang Seok
Hui, Kam Man
Kumar, Alan Prem
Sethi, Gautam

October 2013

Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL in...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma.

Kanjoormana Aryan Manu
Muthu K Shanmugam
Tina H Ong
Aruljothi Subramaniam
Kodappully Sivaraman Siveen
Ekambaram Perumal
Ramar Perumal Samy
Pradeep Bist
Lina H K Lim
Alan Prem Kumar
Kam M Hui
Gautam Sethi

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Kanjoormana Aryan Manu
Muthu K. Shanmugam
Tina H. Ong
Aruljothi Subramaniam
Ekambaram Perumal
Ramar Perumal Samy
Pradeep Bist
Lina H. K. Lim
Alan Prem Kumar
Kam M. Hui
Gautam Sethi

August 2016

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

Manu, K.
Shanmugam, M.
Ong, T.
Subramahniam, A.
Siveen, K.
Perumal, E.
Samy, R.
Bist, P.
Lim, L.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

Subramaniam, Aruljothi
Shanmugam, Muthu K.
Ong, Tina H.
Li, Feng
Perumal, Ekambaram
Chen, Luxi
Vali, Shireen
Abbasi, Taher
Kapoor, Shweta
Ahn, Kwang Seok
Kumar, Alan Prem
Hui, Kam Man
Sethi, Gautam

October 2013

Article on emodin inhibiting growth and inducing apoptosis in an orthotopic hepatocellular carcinoma...

Emodin suppresses CXCR4 in HCC cells.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

A, The chemical structure of emodin. B, Western blot analysis of CXCR4 and HER2 expression in HCC...

Emodin suppresses lung metastasis and CXCR4 expression in orthotopic mice model.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

Spontaneous metastatic model of human liver cancer cells orthotopically implanted in nude mice. C...

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

Chin-Mu Hsu

[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer...

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

Subramaniam, A.
Shanmugam, M.
Ong, T.
Li, F.
Perumal, E.
Chen, L.
Vali, S.
Abbasi, T.
Kapoor, S.
Ahn, K.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

BACKGROUND AND PURPOSE: Aberrant activation of STAT3 is frequently encountered and promotes prolifer...

Emodin suppresses migration and invasion of HepG2 cells.

Kanjoormana Aryan Manu (582759)
Muthu K. Shanmugam (329744)
Tina H. Ong (329745)
Aruljothi Subramaniam (582760)
Kodappully Sivaraman Siveen (582761)
Ekambaram Perumal (582762)
Ramar Perumal Samy (109717)
Pradeep Bist (528101)
Lina H. K. Lim (582763)
Alan Prem Kumar (142201)
Kam M. Hui (137471)
Gautam Sethi (109732)

March 2013

A, Wound-healing assay was performed for evaluating the inhibitory effect of emodin on HepG2 cell...

Emodin represses TWIST1-induced epithelial-mesenchymal transition in head and neck squamous cell carcinoma cells through the inhibition of β-catenin and Akt pathways

Tzong-Der Way

[[abstract]]Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer dea...

Emodin represses TWIST1-induced epithelial-mesenchymal transition in head and neck squamous cell carcinoma cells through the inhibition of β-catenin and Akt pathways

魏宗德

[[abstract]]Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer dea...

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Young-Seon Kim

October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observ...

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Young-Seon Kim
Yoon-Mi Lee
Taek-In Oh
Dong Hoon Shin
Geon-Hee Kim
Sang-Yeon Kan
Hyeji Kang
Ji Hyung Kim
Byeong Mo Kim
Woo Jong Yim
Ji-Hong Lim

October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observ...

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Shrimali, D.
Shanmugam, M.
Kumar, Alan Prem
Zhang, J.
Tan, B.
Ahn, K.
Sethi, G.

January 2013

Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a natural occurring anthraquinone derivative isol...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser Yue
Rajendran, Peramaiyan
Manu, Kanjoormana Aryan
Perumal, Ekambaram
Li, Feng
Shanmugam, Muthu K.
Siveen, Kodappully Sivaraman
Park, Joo In
Ahn, Kwang Seok
Hui, Kam Man
Kumar, Alan Prem
Sethi, Gautam

October 2013

Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL in...

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Abstract

Extracted data

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Abstract

Extracted data

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