An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

Chin-Mu Hsu

[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer...

DataSheet_1_Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin.pdf

Bo Li (112195)
Xin Zhao (71840)
Lei Zhang (38117)
Wen Cheng (134453)

December 2023

Doxorubicin (DOX) is a cytotoxic drug used for the treatment of breast cancer (BC). However, the rap...

Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS

Ke-jie Wang
Xiang-yu Meng
Jun-feng Chen
Kai-yun Wang
Cheng Zhou
Rui Yu
Qi Ma

January 2021

Renal cell carcinoma (RCC) is a tumor with unpredictable presentation and poor clinical outcome. RCC...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser Yue
Rajendran, Peramaiyan
Manu, Kanjoormana Aryan
Perumal, Ekambaram
Li, Feng
Shanmugam, Muthu K.
Siveen, Kodappully Sivaraman
Park, Joo In
Ahn, Kwang Seok
Hui, Kam Man
Kumar, Alan Prem
Sethi, Gautam

May 2013

Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL in...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser
Rajendran, P.
Manu, K.
Permul, E.
Li, F.
Shanmugam, M.
Siveen, K.
Park, J.
Ahn, K.
Hui, K.
Kumar, Alan Prem
Sethi, G.

January 2013

Recombinant tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is currently under clini...

Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes

Li, Wing Yan
Chan, Robbie Yat Kan
Yu, Hoi Fu, Peter
Chan, Shun Wan

January 2013

Context: The poor prognostic outcome of breast cancer is largely due to its resistance to cancer the...

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Lin, Shuw-Yuan

[[abstract]]Emodin was isolated from Rheum palmatum L. and exhibits an anticancer effect on human ca...

Emodin inhibits proliferation and invasion, and induces apoptosis in human esophageal cancer cell line ECA109

Zhao, Chuan
Wu, Youyi
Li, Fuyao
Jin, Xiaosheng

May 2017

Purpose: To determine the anticancer effects of emodin in human esophageal carcinoma cell line ECA10...

Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model

[[abstract]]Emodin, an active natural anthraquinone derivative, is found in the roots and rhizomes o...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

Manu, K.
Shanmugam, M.
Ong, T.
Subramahniam, A.
Siveen, K.
Perumal, E.
Samy, R.
Bist, P.
Lim, L.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin Has Cytotoxic and Protective Effects in Rat C6 Glioma Cells: Roles of Mdr1a and Nuclear Factor kappa B in Cell Survival

Kuo, TC (Kuo, Tzu-Ching)

[[abstract]]1,3,8-Trihydroxy-6-methylanthaquinone (emodin) is recognized as an antiproliferative com...

Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration

Kun Yang
Ming-Ji Jin
Zhe-Shan Quan
Hu-Ri Piao

March 2019

Emodin is a cell arrest and apoptosis-inducing compound that is widely distributed in different plan...

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Lin, Shuw-Yuan

[[abstract]]Emodin was isolated from Rheum palmatum L. and exhibits an anticancer effect on human ca...

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Shrimali, Deepti
Shanmugam, Muthu K.
Kumar, Alan Prem
Zhang, Jingwen
Tan, Benny K-H
Ahn, Kwang Seok
Sethi, Gautam

December 2013

Article on the targeted abrogation of diverse signal transduction cascades by emodin for the treatme...

Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis

Li, WY
Ng, YF
Zhang, H
Guo, ZD
Guo, DJ
Kwan, YW
Leung, GPH
Lee, SMH
Yu, PHF
Chan, SW

January 2014

This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on...

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

Chin-Mu Hsu

[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer...

DataSheet_1_Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin.pdf

Bo Li (112195)
Xin Zhao (71840)
Lei Zhang (38117)
Wen Cheng (134453)

December 2023

Doxorubicin (DOX) is a cytotoxic drug used for the treatment of breast cancer (BC). However, the rap...

Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS

Ke-jie Wang
Xiang-yu Meng
Jun-feng Chen
Kai-yun Wang
Cheng Zhou
Rui Yu
Qi Ma

January 2021

Renal cell carcinoma (RCC) is a tumor with unpredictable presentation and poor clinical outcome. RCC...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser Yue
Rajendran, Peramaiyan
Manu, Kanjoormana Aryan
Perumal, Ekambaram
Li, Feng
Shanmugam, Muthu K.
Siveen, Kodappully Sivaraman
Park, Joo In
Ahn, Kwang Seok
Hui, Kam Man
Kumar, Alan Prem
Sethi, Gautam

May 2013

Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL in...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Subramaniam, Aruljothi
Loo, Ser
Rajendran, P.
Manu, K.
Permul, E.
Li, F.
Shanmugam, M.
Siveen, K.
Park, J.
Ahn, K.
Hui, K.
Kumar, Alan Prem
Sethi, G.

January 2013

Recombinant tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is currently under clini...

Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes

Li, Wing Yan
Chan, Robbie Yat Kan
Yu, Hoi Fu, Peter
Chan, Shun Wan

January 2013

Context: The poor prognostic outcome of breast cancer is largely due to its resistance to cancer the...

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Lin, Shuw-Yuan

[[abstract]]Emodin was isolated from Rheum palmatum L. and exhibits an anticancer effect on human ca...

Emodin inhibits proliferation and invasion, and induces apoptosis in human esophageal cancer cell line ECA109

Zhao, Chuan
Wu, Youyi
Li, Fuyao
Jin, Xiaosheng

May 2017

Purpose: To determine the anticancer effects of emodin in human esophageal carcinoma cell line ECA10...

Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model

[[abstract]]Emodin, an active natural anthraquinone derivative, is found in the roots and rhizomes o...

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

Manu, K.
Shanmugam, M.
Ong, T.
Subramahniam, A.
Siveen, K.
Perumal, E.
Samy, R.
Bist, P.
Lim, L.
Kumar, Alan Prem
Hui, K.
Sethi, G.

January 2013

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the...

Emodin Has Cytotoxic and Protective Effects in Rat C6 Glioma Cells: Roles of Mdr1a and Nuclear Factor kappa B in Cell Survival

Kuo, TC (Kuo, Tzu-Ching)

[[abstract]]1,3,8-Trihydroxy-6-methylanthaquinone (emodin) is recognized as an antiproliferative com...

Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration

Kun Yang
Ming-Ji Jin
Zhe-Shan Quan
Hu-Ri Piao

March 2019

Emodin is a cell arrest and apoptosis-inducing compound that is widely distributed in different plan...

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Lin, Shuw-Yuan

[[abstract]]Emodin was isolated from Rheum palmatum L. and exhibits an anticancer effect on human ca...

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Shrimali, Deepti
Shanmugam, Muthu K.
Kumar, Alan Prem
Zhang, Jingwen
Tan, Benny K-H
Ahn, Kwang Seok
Sethi, Gautam

December 2013

Article on the targeted abrogation of diverse signal transduction cascades by emodin for the treatme...

Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis

Li, WY
Ng, YF
Zhang, H
Guo, ZD
Guo, DJ
Kwan, YW
Leung, GPH
Lee, SMH
Yu, PHF
Chan, SW

January 2014

This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on...

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

Chin-Mu Hsu

[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer...

DataSheet_1_Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin.pdf

Bo Li (112195)
Xin Zhao (71840)
Lei Zhang (38117)
Wen Cheng (134453)

December 2023

Doxorubicin (DOX) is a cytotoxic drug used for the treatment of breast cancer (BC). However, the rap...

Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS

Ke-jie Wang
Xiang-yu Meng
Jun-feng Chen
Kai-yun Wang
Cheng Zhou
Rui Yu
Qi Ma

January 2021

Renal cell carcinoma (RCC) is a tumor with unpredictable presentation and poor clinical outcome. RCC...

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Abstract

Extracted data

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Abstract

Extracted data

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