Add to ORKGSirolimus (SRL) have been pointed as a feasible option for minimize the use of cyclosporine A (CsA), especially because os putatively less nephrotoxicity. However, the cellular mechanism underlying the renoprotection remains to be elucidated, and the clinical data is yet insufficient. This stuty aimed to characterize the histological lesions and the molecular pathways implicated in CsA-induced nephropathy and prevention when converted to SRL
Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, ...
Cyclosporine (CsA) is a potent immunosuppressant used in the prevention of transplant-ed organ rejec...
Background. In this study we tested the hypothesis that sirolimus (a target of rapamycin inhibitor t...
This work was supported by Portuguese Foundation for Science and Technology, Center for Studies in E...
Protocols of conversion from cyclosporin A (CsA) to sirolimus (SRL) have been widely used in immunot...
Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as n...
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms under...
Copyright © 2014 Jose ́ Sereno et al. This is an open access article distributed under the Creative ...
Cyclosporin (CsA) has been progressively replaced by other drugs with putatively fever side effects,...
Protocols of conversion from cyclosporine A (CsA) to sirolimus (SRL) have been widely used in immuno...
Sirolimus increases transforming growth factor-β1 expression and potentiates chronic cyclosporine ne...
Sirolimus, a macrocylic lactone, blocks T-cell activation by a mechanism of action distinct from cal...
Calcineurin inhibitors exacerbate ischemic injury in transplanted kidneys, but it is not known if si...
Background: Ischemia-reperfusion (I/R) is present at various degrees in kidney transplants. I/R play...
Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, ...
Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, ...
Cyclosporine (CsA) is a potent immunosuppressant used in the prevention of transplant-ed organ rejec...
Background. In this study we tested the hypothesis that sirolimus (a target of rapamycin inhibitor t...
This work was supported by Portuguese Foundation for Science and Technology, Center for Studies in E...
Protocols of conversion from cyclosporin A (CsA) to sirolimus (SRL) have been widely used in immunot...
Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as n...
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms under...
Copyright © 2014 Jose ́ Sereno et al. This is an open access article distributed under the Creative ...
Cyclosporin (CsA) has been progressively replaced by other drugs with putatively fever side effects,...
Protocols of conversion from cyclosporine A (CsA) to sirolimus (SRL) have been widely used in immuno...
Sirolimus increases transforming growth factor-β1 expression and potentiates chronic cyclosporine ne...
Sirolimus, a macrocylic lactone, blocks T-cell activation by a mechanism of action distinct from cal...
Calcineurin inhibitors exacerbate ischemic injury in transplanted kidneys, but it is not known if si...
Background: Ischemia-reperfusion (I/R) is present at various degrees in kidney transplants. I/R play...
Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, ...
Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, ...
Cyclosporine (CsA) is a potent immunosuppressant used in the prevention of transplant-ed organ rejec...
Background. In this study we tested the hypothesis that sirolimus (a target of rapamycin inhibitor t...