Effect of vitamin E supplementation on immune status and alpha -tocopherol in plasma of piglets

From day 57 of pregnancy, 12 Yorkshire gilts were given a diet without and with 5% rapeseed oil, supplemented with Se 0.1 mg and DL- alpha -tocopherol (as tocopherol acetate) 22 IU/kg feed. Colostrum (day 0) and milk (days 7, 14, 21 and 28 post partum) were sampled from gilts. At farrowing, 3 piglets from each gilt of both groups were injected with alpha -tocopherol 500 IU at birth and 1000 IU at 7 and 14 days old; 3 piglets were injected with saline and used as controls. Blood samples were taken from the newborn piglets at birth and at 7, 14, 21, 28 and 35 days old. alpha -Tocopherol concentrations and antibody titres in colostrum were significantly higher than in the milk. Plasma alpha -tocopherol concentrations and antibody titres to Keyhole limpet haemocyanin of piglets injected with tocopherol were significantly higher than controls. Tocopherol-injected piglets had significantly higher alpha -tocopherol concentrations in spleen, liver, kidney, heart, lung and hip muscle than controls..RE: 21 ref.; RN: 7782-49-2; 1406-18-4; SC: ZA; VE; BE; CA; 0I; 0N; 7D; 0V; 0DSource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0926-5287&isbn=&volume=35&issue=4&spage=443&pages=443-450&date=1995&title=Reproduction%2c%20Nutrition%2c%20Development&atitle=Effect%20of%20vitamin%20E%20supplementation%20on%20immune%20status%20and%20%20alpha%20-tocopherol%20in%20plasma%20of%20piglets.&aulast=Hidiroglou&pid=%3Cauthor%3EHidiroglou%2c%20M%3bBatra%2c%20T%20R%3bFarnworth%2c%20E%20R%3bMarkham%2c%20F%3C%2Fauthor%3E%3CAN%3E19951412504%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3