In vitro immunoregulatory effects of lithium in healthy volunteers

DOI

10.1007/s002130050965

Publisher

Springer Science and Business Media LLC

ISSN

0033-3158

Citation count (estimate)

Abstract

Examined the in vitro effects of lithium carbonate on the unstimulated and lipolysaccharide (LPS)?+?phytohemagglutinin (PHA)-induced production of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-8, tumor necrosis factor-? (TNF?) and interferon-? (IFN?), and negative immunoregulatory cytokines or proteins, such as IL-10 and the IL-1 receptor antagonist (IL-1RA)