Long-term changes of nutrients intake and changes of cardiovascular risk factors

科学研究費補助金研究成果報告書研究種目: 基盤研究(B)研究期間: 2008～2010課題番号: 20390188研究代表者: 三浦 克之（滋賀医科大学・医学部・教授）某製造業事業所の従業員を対象に2009年に栄養調査を実施し6,705名から回答を得た.2003年の結果と比較すると,脂質,肉類,若年男性の食塩の摂取量は増加し,中高年の食塩,魚介類は減少していた.個人の栄養素・食品摂取の変化量と臨床検査値の変化量との関連において,男性では,脂肪摂取量とLDLコレステロール,肉類とBMIとの間に正の関連,食物繊維と中性脂肪,緑黄色野菜と総コレステロールの間に負の関連を,女性では総熱量と中性脂肪,脂肪摂取量と総コレステロールとの間に正の関連を認めた.栄養素・食品摂取量の長期的な変化は生活習慣病発現に影響する可能性が示されたParticipants were 6,705 employees of a metal products factory in Japan. Dietary intake for foods and nutrients were assessed two times in 2003 and 2009 using a self-administered diet history questionnaire. Dietary intakes of fat, meats for all participants and salt for younger men were higher, and intakes of salt and fish for middle-aged men and women were lower in 2009 compared to 2003 survey. When we evaluated associations between 6-year changes of foods/nutrients intake and changes of metabolic parameters, positive associations between total fat intake and LDL-cholesterol, between meats intake and BMI, and inverse associations between fiber intake and triglycerides, and between green and yellow vegetables intake and total cholesterol were observed for men, and positive associations between total energy and triglycerides, and between fat intake and total cholesterol were observed for women. These results indicated that long-term change of foods/nutrients intakes would affected the changes of cardiovascular risk factors