[[abstract]]Restenosis is resulted from the proliferation and migration of vascular smooth muscle cells (VSMCs) from the arterial media into the intima within the vessel lumen following percutaneous transluminal coronary angioplasty (PTCA). OSU-03012, a synthetic compound (2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide) acting as a PDK-1 inhibitor, is used as an apoptosis-promoting anticancer drug. However, whether OSU-03012 can inhibit VSMC proliferation and migration following PTCA remains unclear. In this study, we used A10 smooth muscle cells cultured in 10% FBS for stimulating proliferation and evaluated the inhibitory effects of OSU-03012 on cell proliferation and migration. The data demonstra...
Background/Aims: Phorbol myristate acetate (PMA) exerts a pleiotropic effect on the growth and diffe...
Abnormal migration and proliferation of vascular smooth mus-cle cells (VSMCs) are key events in the ...
OBJECTIVE: Drug-eluting coronary stents reduce restenosis rate and late lumen loss compared with bar...
Abstract Background Pathologic vascular smooth muscle cell (VSMC) proliferation and migration afte...
Percutaneous transluminal coronary angioplasty (PTCA) has greatly benefited patients with occluded c...
Objectives. To observe the effect of avβ3 single-stranded (ss) DNA on proliferation and migration of...
Purpose: Vascular smooth muscle cell (VSMC) proliferation plays a critical role in the pathogenesis ...
Abstract Background Pathologic...
Smooth muscle cell proliferation plays an important role in neointimal thickening after vascular inj...
Objective: Abnormal proliferation or migration of vascular smooth muscle cells (VSMCs) can lead to v...
Background—Although percutaneous transluminal coronary angioplasty (PTCA) is a highly effective proc...
Atherosclerosis is the principal cause of myocardial infarction, stroke, and peripheral vascular dis...
Atherosclerosis is the principal cause of myocardial infarction, stroke, and peripheral vascular dis...
Background/Aims: Abnormal proliferation of vascular smooth muscle cells (VSMCs) is a hallmark of vas...
Increasing evidence showed that abnormal proliferation and migration of vascular smooth muscle cells...
Background/Aims: Phorbol myristate acetate (PMA) exerts a pleiotropic effect on the growth and diffe...
Abnormal migration and proliferation of vascular smooth mus-cle cells (VSMCs) are key events in the ...
OBJECTIVE: Drug-eluting coronary stents reduce restenosis rate and late lumen loss compared with bar...
Abstract Background Pathologic vascular smooth muscle cell (VSMC) proliferation and migration afte...
Percutaneous transluminal coronary angioplasty (PTCA) has greatly benefited patients with occluded c...
Objectives. To observe the effect of avβ3 single-stranded (ss) DNA on proliferation and migration of...
Purpose: Vascular smooth muscle cell (VSMC) proliferation plays a critical role in the pathogenesis ...
Abstract Background Pathologic...
Smooth muscle cell proliferation plays an important role in neointimal thickening after vascular inj...
Objective: Abnormal proliferation or migration of vascular smooth muscle cells (VSMCs) can lead to v...
Background—Although percutaneous transluminal coronary angioplasty (PTCA) is a highly effective proc...
Atherosclerosis is the principal cause of myocardial infarction, stroke, and peripheral vascular dis...
Atherosclerosis is the principal cause of myocardial infarction, stroke, and peripheral vascular dis...
Background/Aims: Abnormal proliferation of vascular smooth muscle cells (VSMCs) is a hallmark of vas...
Increasing evidence showed that abnormal proliferation and migration of vascular smooth muscle cells...
Background/Aims: Phorbol myristate acetate (PMA) exerts a pleiotropic effect on the growth and diffe...
Abnormal migration and proliferation of vascular smooth mus-cle cells (VSMCs) are key events in the ...
OBJECTIVE: Drug-eluting coronary stents reduce restenosis rate and late lumen loss compared with bar...