The Adler sum rule for deep inelastic neutrino scattering measures the isospin of the nucleon and is hence exact. By contrast, the corresponding Gottfried sum rule for charged lepton scattering was based merely on a valence picture and is modified both by perturbative and by non-perturbative effects. Noting that the known perturbative corrections to two-loop order are suppressed by a factor 1/Nc2, relative to those for higher moments, we propose that this suppression persists at higher orders and also applies to higher-twist effects. Moreover, we propose that the differences between the corresponding radiative corrections to higher non-singlet moments in charged-lepton and neutrino deep inelastic scattering are suppressed by 1/Nc2, in all o...